Title:
METHOD FOR PRODUCING DEAD LACTIC ACID BACTERIA CELLS HAVING ENHANCED IMMUNOREGULATORY FUNCTION
Document Type and Number:
WIPO Patent Application WO/2024/029958
Kind Code:
A1
Abstract:
The present application relates to: a method for producing dead lactic acid bacteria cells, comprising a step of performing primary heat treatment and secondary heat treatment on any one or more lactic acid bacteria selected from the group consisting of the strains of Lactobacillus plantarum CJLP133 deposited with accession number KCTC 11403BP, Lactobacillus plantarum CJLP243 deposited with accession number KCCM 11045P, and Lactobacillus plantarum CJLP55 deposited with accession number KCTC 11401BP; a method for increasing the immunoregulatory function of dead lactic acid bacteria cells; a method for increasing an interferon gamma production ability or an interleukin-4 reduction ability of dead lactic acid bacteria cells; a method for increasing the ability to inhibit the attachment of harmful intestinal bacteria; dead lactic acid bacteria cells produced thereby; and an immunoregulatory food, pharmaceutical and feed composition, which include the dead lactic acid bacteria cells.
Inventors:
PARK JAE SEUNG (KR)
JUNG WOO-YONG (KR)
JUNG HEE KYOUNG (KR)
YUN HYUN SUN (KR)
LEE JAYOUNG (KR)
KIM MIN-SU (KR)
JUNG WOO-YONG (KR)
JUNG HEE KYOUNG (KR)
YUN HYUN SUN (KR)
LEE JAYOUNG (KR)
KIM MIN-SU (KR)
Application Number:
PCT/KR2023/011409
Publication Date:
February 08, 2024
Filing Date:
August 03, 2023
Export Citation:
Assignee:
CJ WELLCARE CORP (KR)
International Classes:
C12N1/20; A23K10/16; A23L33/135; A61K35/747; A61P37/02; C12N1/36; C12R1/25
Foreign References:
| KR20110009560A | 2011-01-28 | |||
| KR20110046020A | 2011-05-04 | |||
| KR20110006455A | 2011-01-20 | |||
| KR20210073823A | 2021-06-21 |
Other References:
LEE JAESUNG, KALETUNÇ GÖNÜL: "Evaluation of the Heat Inactivation of Escherichia coli and Lactobacillus plantarum by Differential Scanning Calorimetry", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 68, no. 11, 1 November 2002 (2002-11-01), US , pages 5379 - 5386, XP093135134, ISSN: 0099-2240, DOI: 10.1128/AEM.68.11.5379-5386.2002
ZIELIŃSKA DOROTA, ŁEPECKA ANNA, OŁDAK ALEKSANDRA, DŁUGOSZ EWA, KOŁOŻYN-KRAJEWSKA DANUTA: "Growth and adhesion inhibition of pathogenic bacteria by live and heat-killed food-origin Lactobacillus strains or their supernatants", FEMS MICROBIOLOGY LETTERS AUG 2009, vol. 368, no. 5, 1 March 2021 (2021-03-01), pages fnab024, XP093135136, ISSN: 1574-6968, DOI: 10.1093/femsle/fnab024
ZIELIŃSKA DOROTA, ŁEPECKA ANNA, OŁDAK ALEKSANDRA, DŁUGOSZ EWA, KOŁOŻYN-KRAJEWSKA DANUTA: "Growth and adhesion inhibition of pathogenic bacteria by live and heat-killed food-origin Lactobacillus strains or their supernatants", FEMS MICROBIOLOGY LETTERS AUG 2009, vol. 368, no. 5, 1 March 2021 (2021-03-01), pages fnab024, XP093135136, ISSN: 1574-6968, DOI: 10.1093/femsle/fnab024
Attorney, Agent or Firm:
HANOL INTELLECTUAL PROPERTY AND LAW (KR)
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