Title:
METHOD FOR PRODUCING LACTAM
Document Type and Number:
WIPO Patent Application WO/2016/167519
Kind Code:
A1
Abstract:
The present invention relates to a recombinant microorganism having a lactam production capacity from omega-amino acid, into which a gene for coating a beta-alanine coenzyme A transferase on a microorganism having an omega-amino acid biosynthetic metabolic pathway from amino acid is introduced, and a method for producing a variety of lactams and omega-aminoacyl-CoAs using the same. The recombinant microorganism and the method for producing lactam according to the present invention are useful in producing a variety of lactams such as propiolactam, 2-pyrrolidone, valerolactam, carprolactam, heptanolactam, etc. from a variety of omega-amino acids.
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Inventors:
LEE SANG YUP (KR)
CHAE TONG UN (KR)
SONG CHAN WOO (KR)
CHAE TONG UN (KR)
SONG CHAN WOO (KR)
Application Number:
PCT/KR2016/003758
Publication Date:
October 20, 2016
Filing Date:
April 11, 2016
Export Citation:
Assignee:
KOREA ADVANCED INST SCI & TECH (KR)
International Classes:
C12N15/63; C12N9/02; C12N9/10; C12N9/78; C12P17/18
Foreign References:
| KR20120034640A | 2012-04-12 | |||
| US8592189B2 | 2013-11-26 | |||
| US20100324257A1 | 2010-12-23 |
Other References:
HERRMANN, GLORIA ET AL.: "Two Beta-alanyl-CoA: Ammonia Lyases in Clostridium Propionicum", THE FEBS JOURNAL, vol. 272, no. 3, 2005, pages 813 - 821, XP055324319
KOETSIER, MARTIJN J. ET AL.: "Aminoacyl-coenzyme A Synthesis Catalyzed by a CoA Ligase from Penicillium Chrysogenum", FEBS LETTERS, vol. 585, no. 6, 18 February 2011 (2011-02-18), pages 893 - 898, XP028198632
KOETSIER, MARTIJN J. ET AL.: "Aminoacyl-coenzyme A Synthesis Catalyzed by a CoA Ligase from Penicillium Chrysogenum", FEBS LETTERS, vol. 585, no. 6, 18 February 2011 (2011-02-18), pages 893 - 898, XP028198632
Attorney, Agent or Firm:
LEE, Cheo Young et al. (KR)
이처영 (KR)
이처영 (KR)
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