Title:
METHOD FOR PRODUCING MALEIMIDE POLYETHYLENE GLYCOL DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2022/131098
Kind Code:
A1
Abstract:
The present invention is a method for producing a maleimide polyethylene glycol derivative which comprises a reaction step for de-protecting a maleimide polyethylene glycol derivative having a protective group by heating in a solvent and in the presence of silica gel. The present invention makes it possible, when de-protecting a maleimide polyethylene glycol derivative having a protective group, to suppress deterioration of a maleimide group and to produce a maleimide polyethylene glycol derivative which has a high maleimidization rate.
Inventors:
OZONE DAIKI (JP)
MORI SHOTA (JP)
OTA MASAKI (JP)
MORI SHOTA (JP)
OTA MASAKI (JP)
Application Number:
PCT/JP2021/045098
Publication Date:
June 23, 2022
Filing Date:
December 08, 2021
Export Citation:
Assignee:
NOF CORP (JP)
International Classes:
C08G65/333
Domestic Patent References:
| WO2005056636A2 | 2005-06-23 | |||
| WO2012133490A1 | 2012-10-04 |
Foreign References:
| JP2011225860A | 2011-11-10 | |||
| JPS61122241A | 1986-06-10 |
Other References:
BIOCONJUGATE CHEM., vol. 14, no. 2, 2003, pages 377 - 387
Attorney, Agent or Firm:
TAGUCHI, Masahiro et al. (JP)
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