Title:
METHOD FOR PRODUCING NEURAL CELLS
Document Type and Number:
WIPO Patent Application WO/2019/107354
Kind Code:
A1
Abstract:
Provided is a method for producing neural cells, the method including: preparing stems cells; and introducing Sendai virus into the stem cells via infection, and causing the Sendai virus to express induction-factor-synthesizing mRNA within the stem cells to induce the stem cells into neural cells.
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Inventors:
TANABE KOJI (US)
INOUE MAKOTO (JP)
SHU TSUGUMINE (JP)
MORI TOYOTAKA (JP)
INOUE MAKOTO (JP)
SHU TSUGUMINE (JP)
MORI TOYOTAKA (JP)
Application Number:
PCT/JP2018/043573
Publication Date:
June 06, 2019
Filing Date:
November 27, 2018
Export Citation:
Assignee:
I PEACE INC (US)
ID PHARMA CO LTD (JP)
ID PHARMA CO LTD (JP)
International Classes:
C12N15/83
Domestic Patent References:
| WO2016163958A1 | 2016-10-13 | |||
| WO2014148646A1 | 2014-09-25 | |||
| WO2017209290A1 | 2017-12-07 |
Foreign References:
| JP2018143239A | 2018-09-20 |
Other References:
GOTO, KAZUYA ET AL.: "Simple Derivation of Spinal Motor Neurons from ESCs/iPSCs using Sendai Virus Vectors", MOLECULAR THERAPY: METHODS & CLINICAL DEVELOPMENT, vol. 4, 10 January 2017 (2017-01-10) - March 2017 (2017-03-01), pages 115 - 125, XP055615587
NATURE BIOTECHNOL., vol. 26, no. 3, 2008, pages 313 - 315
PNAS, vol. 111, 2014, pages 12426 - 12431
N ENG J MED, vol. 346, 2002, pages 1185 - 1193
SCIENCE, vol. 302, 2003, pages 415 - 419
See also references of EP 3719133A4
NATURE BIOTECHNOL., vol. 26, no. 3, 2008, pages 313 - 315
PNAS, vol. 111, 2014, pages 12426 - 12431
N ENG J MED, vol. 346, 2002, pages 1185 - 1193
SCIENCE, vol. 302, 2003, pages 415 - 419
See also references of EP 3719133A4
Attorney, Agent or Firm:
INABA, Yoshiyuki et al. (JP)
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