Title:
METHOD FOR PRODUCING PHYTOSPHINGOSINE OR PHYTOCERAMIDE
Document Type and Number:
WIPO Patent Application WO/2022/158534
Kind Code:
A1
Abstract:
A method for producing an objective substance, such as phytosphingosine (PHS) and phytoceramide (PHC), comprising a desired alkyl chain using yeast is provided. An objective substance is produced by cultivating yeast having an ability to produce the objective substance in a culture medium containing a fatty acid.
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Inventors:
SEREBRIANYI VSEVOLOD ALEKSANDROVICH (RU)
SOFYANOVICH OLGA ALEKSANDROVNA (RU)
OZEROVA ANNA MIKHAILOVNA (RU)
KAKIYAMA TAKASHI (JP)
HIRATSUKA NOBUHIRO (JP)
TATEYAMA YASUHIRO (JP)
WIRDNAM CORINA (CH)
TAVARES SABINA DE ANDRADE PEREIRA (CH)
SCHWAB MARKUS (CH)
SOFYANOVICH OLGA ALEKSANDROVNA (RU)
OZEROVA ANNA MIKHAILOVNA (RU)
KAKIYAMA TAKASHI (JP)
HIRATSUKA NOBUHIRO (JP)
TATEYAMA YASUHIRO (JP)
WIRDNAM CORINA (CH)
TAVARES SABINA DE ANDRADE PEREIRA (CH)
SCHWAB MARKUS (CH)
Application Number:
PCT/JP2022/002033
Publication Date:
July 28, 2022
Filing Date:
January 20, 2022
Export Citation:
Assignee:
AJINOMOTO KK (JP)
EVOLVA SA (CH)
EVOLVA SA (CH)
International Classes:
C12P13/00; C12P13/02
Domestic Patent References:
| WO1994010131A1 | 1994-05-11 | |||
| WO2017033464A1 | 2017-03-02 | |||
| WO1995032289A1 | 1995-11-30 | |||
| WO2017033463A1 | 2017-03-02 | |||
| WO2017033464A1 | 2017-03-02 |
Foreign References:
| US5869711A | 1999-02-09 |
Other References:
DATABASE WPI Week 202007, Derwent World Patents Index; AN 2020-84761G, XP055933352, "New recombinant plasmid useful for promoting transport of oil or fatty acid across cell membranes for improving production of precursor metabolites, preferably naringenin or ceramide, comprises caveolin gene"
DATABASE WPI Week 201632, Derwent World Patents Index; AN 2016-25596Q, XP055933338, "New modified Starmerella genus microorganism, preferably Starmerella bombicola useful for preparing acetylated sphingoid, obtained by introducing gene encoding polypeptide having acetyltransferase activity"
ACTA DERM VENEREOL., vol. 82, no. 3, 2002, pages 170 - 3
PLANT CELL., vol. 18, no. 12, December 2006 (2006-12-01), pages 3576 - 93
J BIOL CHEM., vol. 275, no. 11, 17 March 2000 (2000-03-17), pages 7597 - 603
BIOCHIM BIOPHYS ACTA., vol. 1761, no. 1, January 2006 (2006-01-01), pages 52 - 63
SU WM, J BIOL CHEM., vol. 289, no. 50, 12 December 2014 (2014-12-12), pages 34699 - 708
J BIOL CHEM., vol. 278, no. 9, 28 February 2003 (2003-02-28), pages 7325 - 34
PLANT PHYSIOL., vol. 137, no. 2, February 2005 (2005-02-01), pages 724 - 37
J BIOL CHEM., vol. 272, no. 28, 11 July 1997 (1997-07-11), pages 17376 - 84
EUKARYOT CELL, vol. 2, no. 2, April 2003 (2003-04-01), pages 284 - 94
GENE, vol. 192, no. 2, 19 June 1997 (1997-06-19), pages 245 - 50
EUR J BIOCHEM., vol. 123, no. 3, April 1982 (1982-04-01), pages 571 - 6
MILLER, J.H.: "Experiments in Molecular Genetics", 1972, COLD SPRING HARBOR LABORATORY
"Genetic Engineering", vol. 8, 1987, KYORITSU SHUPPAN CO., LTD, article "Fundamental Microbiology"
GENE, vol. 60, no. 1, 1987, pages 115 - 127
NAKAMURA, Y. ET AL., NUCL. ACIDS RES., vol. 28, 2000, pages 292, Retrieved from the Internet
H.ITO ET AL., J. BATERIOL., 1983, pages 153 - 163
FERMENTATION AND INDUSTRY, vol. 43, 1985, pages 630 - 637
LUIS ET AL., FEMS MICRO BIOLOGY LETTERS, vol. 165, 1998, pages 335 - 340
GIETZ R.D.SCHIESTL R.H., METHODS MOL.CELL. BIOL., vol. 5, 1995, pages 255 - 269
"Chemistry and Biology", HIROKAWA-SHOTEN, article "Experimental Line 31, Experimental Techniques for Yeast"
"Bio-Manual", YODOSHA, article "Genetic Experimental Methods for Yeast"
SAMBROOK, J. ET AL.: "Molecular Cloning A Laboratory Manual", 2001, COLD SPRING HARBOR LABORATORY PRESS
JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 272, 1997, pages 8611 - 8617
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, USA, vol. 95, 1998, pages 5511 - 5515
JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 26, no. 116, 1991, pages 20833 - 20839
DATABASE WPI Week 201632, Derwent World Patents Index; AN 2016-25596Q, XP055933338, "New modified Starmerella genus microorganism, preferably Starmerella bombicola useful for preparing acetylated sphingoid, obtained by introducing gene encoding polypeptide having acetyltransferase activity"
ACTA DERM VENEREOL., vol. 82, no. 3, 2002, pages 170 - 3
PLANT CELL., vol. 18, no. 12, December 2006 (2006-12-01), pages 3576 - 93
J BIOL CHEM., vol. 275, no. 11, 17 March 2000 (2000-03-17), pages 7597 - 603
BIOCHIM BIOPHYS ACTA., vol. 1761, no. 1, January 2006 (2006-01-01), pages 52 - 63
SU WM, J BIOL CHEM., vol. 289, no. 50, 12 December 2014 (2014-12-12), pages 34699 - 708
J BIOL CHEM., vol. 278, no. 9, 28 February 2003 (2003-02-28), pages 7325 - 34
PLANT PHYSIOL., vol. 137, no. 2, February 2005 (2005-02-01), pages 724 - 37
J BIOL CHEM., vol. 272, no. 28, 11 July 1997 (1997-07-11), pages 17376 - 84
EUKARYOT CELL, vol. 2, no. 2, April 2003 (2003-04-01), pages 284 - 94
GENE, vol. 192, no. 2, 19 June 1997 (1997-06-19), pages 245 - 50
EUR J BIOCHEM., vol. 123, no. 3, April 1982 (1982-04-01), pages 571 - 6
MILLER, J.H.: "Experiments in Molecular Genetics", 1972, COLD SPRING HARBOR LABORATORY
"Genetic Engineering", vol. 8, 1987, KYORITSU SHUPPAN CO., LTD, article "Fundamental Microbiology"
GENE, vol. 60, no. 1, 1987, pages 115 - 127
NAKAMURA, Y. ET AL., NUCL. ACIDS RES., vol. 28, 2000, pages 292, Retrieved from the Internet
H.ITO ET AL., J. BATERIOL., 1983, pages 153 - 163
FERMENTATION AND INDUSTRY, vol. 43, 1985, pages 630 - 637
LUIS ET AL., FEMS MICRO BIOLOGY LETTERS, vol. 165, 1998, pages 335 - 340
GIETZ R.D.SCHIESTL R.H., METHODS MOL.CELL. BIOL., vol. 5, 1995, pages 255 - 269
"Chemistry and Biology", HIROKAWA-SHOTEN, article "Experimental Line 31, Experimental Techniques for Yeast"
"Bio-Manual", YODOSHA, article "Genetic Experimental Methods for Yeast"
SAMBROOK, J. ET AL.: "Molecular Cloning A Laboratory Manual", 2001, COLD SPRING HARBOR LABORATORY PRESS
JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 272, 1997, pages 8611 - 8617
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, USA, vol. 95, 1998, pages 5511 - 5515
JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 26, no. 116, 1991, pages 20833 - 20839
Attorney, Agent or Firm:
IP FIRM SHUWA (JP)
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