METHOD FOR PRODUCING QUINOLINE-4(1H)-ONE DERIVATIVE

Title:

METHOD FOR PRODUCING QUINOLINE-4(1H)-ONE DERIVATIVE

Document Type and Number:

WIPO Patent Application WO/2019/117179

Kind Code:

A1

Abstract:

[Problem] To provide a method for producing and isolating a target quinolone derivative using general industrial facilities with high purity. [Solution] The present invention provides a method for producing a quinolone derivative, the method comprising performing a reaction between a ketone and an anthranilic acid derivative using an aluminium halide and removing the aluminium halide under a basic condition.

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Inventors:

MORIKAWA AKINORI (JP)
KURODA HIROKAZU (JP)
YAMAMOTO KAZUMI (JP)
NAKANISHI NOZOMU (JP)

Application Number:

PCT/JP2018/045596

Publication Date:

June 20, 2019

Filing Date:

December 12, 2018

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Assignee:

NIPPON KAYAKU KK (JP)
MEIJI SEIKA PHARMA CO LTD (JP)

International Classes:

C07D215/233

Domestic Patent References:

WO2010007964A1

2010-01-21

Foreign References:

JP2005501104A

2005-01-13

Attorney, Agent or Firm:

NAGAI Hiroshi et al. (JP)

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