METHOD FOR PRODUCING REAGENT FOR ANTIBODY DETECTION AND USE THEREOF

WIPO Patent Application WO/2013/147233

A1

The present invention provides the following: a method for efficiently producing a reagent for detecting an antibody that specifically binds with an insoluble antigen protein present in a liquid sample; a reagent for antibody detection produced by the production method; and a use of the antibody. In a step for solubilizing an antigen protein, it is possible to efficiently solubilize and recover the antigen protein by using a cationizing agent; therefore, when compared to conventional methods, it is possible to efficiently produce a reagent for detecting an antibody that has bound to multiple antigen protein molecules in a carrier.

FUTAMI JUNICHIRO (JP)
KAKIMI KAZUHIRO (JP)
MAEKAWA RYUJI (JP)
SHIRAKI MASATO (JP)

PCT/JP2013/059692

October 03, 2013

March 29, 2013

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UNIV OKAYAMA NAT UNIV CORP (JP)
MEDINET CO LTD (JP)

G01N33/543; C07K14/705; C07K14/82; C07K17/00; G01N33/574

WO2011118731A1	2011-09-29
WO2011118731A1	2011-09-29

JP2008002961A	2008-01-10
JP2010509602A	2010-03-25
JP3960614B2	2007-08-15
JP2005098877A	2005-04-14
JP3225468B2	2001-11-05
JP2010070804A	2010-04-02

M. SENO ET AL., GROWTH FACTORS, vol. 15, 1998, pages 215 - 229
M. INOUE ET AL., BIOTECHNOL. APPL. BIOCHEM., vol. 28, 1998, pages 207 - 213
BIOTECHNOL. APPL. BIOCHEM., vol. 28, 1998, pages 207 - 213
See also references of EP 2833143A4

ASAMURA PATENT OFFICE, p. c. (JP)
Patent business corporation Asamura patent firm (JP)

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