METHOD FOR PRODUCING STERILIZED VISCOUS BASE AND METHOD FOR PRODUCING MEDICINAL PREPARATION - UNIV OSAKA RES FOUND FOR MICROBIAL DISEASES

Title:

METHOD FOR PRODUCING STERILIZED VISCOUS BASE AND METHOD FOR PRODUCING MEDICINAL PREPARATION

Document Type and Number:

WIPO Patent Application WO/2019/022182

Kind Code:

A1

Abstract:

Provided is a method whereby a sterilized viscous base can be easily produced at a high sterilization efficiency. The method for producing a sterilized viscous base (base no. 5) comprises: a heat sterilization step for heat sterilizing an acidic solution of a viscosity-imparting agent (base no. 2) which shows a higher viscosity in a neutral range than in an acidic range; and a neutralization step for, after the heat sterilization step, neutralizing the heat sterilized product (base no. 3) of the acidic solution of the viscosity-imparting agent by adding a base thereto.

Inventors:

MINAMI KOHJI (JP)
GOMI YASUYUKI (JP)
OGAWA HIRONOBU (JP)
YAMAMOTO MAMI (JP)
KONDO TETSUYA (JP)

Application Number:

PCT/JP2018/028038

Publication Date:

January 31, 2019

Filing Date:

July 26, 2018

Export Citation:

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Assignee:

UNIV OSAKA RES FOUND FOR MICROBIAL DISEASES (JP)

International Classes:

A61K9/08; A61K39/00; A61K45/00; A61K47/18; A61K47/32; A61P37/04

Foreign References:

JPH09508907A	1997-09-09
JPH10508316A	1998-08-18
JPH0338529A	1991-02-19