METHOD FOR PRODUCING TARGET SUBSTANCE BY BACTERIAL FERMENTATION

WIPO Patent Application WO/2020/071538

A1

The present invention provides a method for producing a target substance, the biosynthetic pathway of which is ATP-dependent, such as, for example, amino acids, nucleosides, nucleotides, isoprenoids, and peptides, by fermentation of a bacterium which has been modified to overexpress a gene encoding a protein having H+-translocating membrane-bound pyrophosphatase activity, such as, for example, the hppA gene native to R. rubrum or a variant thereof.

ANDRIANOVA EKATERINA (RU)
KHARCHENKO MARIA (RU)
ZAKATAEVA NATALIA (RU)
VOROSHILOVA ELVIRA (RU)
KRYLOV ALEKSANDER (RU)
MALYKH EVGENIYA (RU)
MASHKO SERGEI (RU)
STOYNOVA NATALIA (RU)
BABOSHIN MIKHAIL (RU)
GOLUBEVA LYUBOV (RU)
KOVALEVA EKATERINA (RU)
SHUPLETSOV MIKHAIL (RU)

PCT/JP2019/039297

April 09, 2020

October 04, 2019

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AJINOMOTO KK (JP)

C12N9/14; C12P5/00; C12P13/04; C12P13/24; C12P19/38

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