Title:
METHOD FOR PRODUCING Ω3 AND Ω6 UNSATURATED FATTY ACID OXIDES
Document Type and Number:
WIPO Patent Application WO/2018/003569
Kind Code:
A1
Abstract:
Provided is a method for producing an unsaturated fatty acid oxide (e.g. ω3 fatty acid oxide) that is new and has more beneficial features compared to conventional technologies. This method uses a lipoxygenase-containing composition (e.g. a lipoxygenase-containing composition derived from beans) as a lipoxygenase enzyme, and also uses a freezing method for organic solvent extraction. The present invention makes it possible to produce an unsaturated fatty acid oxide (e.g. ω3 fatty acid oxide) efficiently and at a low cost. The present invention also provides a pharmaceutical composition containing an ω3 fatty acid oxide isolated and purified by this method as an effective ingredient.
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Inventors:
SAITO SHIHO (JP)
MISAWA YOSHIHISA (JP)
BABA NAOMICHI (JP)
TABATA HIROSHI (JP)
TSUSHIMA TADAHIRO (JP)
FUJII JUN (JP)
MISAWA YOSHIHISA (JP)
BABA NAOMICHI (JP)
TABATA HIROSHI (JP)
TSUSHIMA TADAHIRO (JP)
FUJII JUN (JP)
Application Number:
PCT/JP2017/022524
Publication Date:
January 04, 2018
Filing Date:
June 19, 2017
Export Citation:
Assignee:
BIZEN CHEMICAL CO LTD (JP)
International Classes:
C12P7/62; A23L33/12; A61K31/202; A61K31/232; A61K36/48; A61P3/04; A61P3/10; A61P9/10; C07C51/47; C07C59/42
Domestic Patent References:
| WO2015111699A1 | 2015-07-30 | |||
| WO2015063617A2 | 2015-05-07 |
Foreign References:
| JPH07291862A | 1995-11-07 | |||
| JPH07500252A | 1995-01-12 |
Other References:
XIANG LI ET AL.: "Docosahexanoic Acid-Induced Coronary Arterial Dilation: Actions of 17S-Hydroxy Docosahexanoic Acid on K+ Channel Activity", THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, vol. 336, no. 3, 2011, pages 891 - 899, XP055601114
Attorney, Agent or Firm:
YAMAMOTO Shusaku et al. (JP)
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