Title:
METHOD FOR PRODUCING VITAMIN D DERIVATIVE UTILIZING PHOTOREACTION
Document Type and Number:
WIPO Patent Application WO/2007/063930
Kind Code:
A1
Abstract:
Disclosed is a novel method for producing [{(5Z,7E)-(1S,3R,20S)-1,3-dihydroxy-9,10-secopregna-5,7,10(19),16-tetraen-20-yl}oxy]-N-(2,2,3,3,3-pentafluoropropyl) acetamide
which is characterized by ring-opening a compound represented by the following
formula: [Chemical formula 1] by irradiation of ultraviolet light, and then
isomerizing the resulting ring-opened compound. Also disclosed are an intermediate
useful for such a production method, and a method for producing such an intermediate.
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Inventors:
KAWASE AKIRA (JP)
KATO YASUHARU (JP)
KINOSHITA KAZUTOMO (JP)
KITOH YASUSHI (JP)
IKEDA TAKUMA (JP)
HANEISHI TSUYOSHI (JP)
MARUYAMA NORIAKI (JP)
KOBAYASHI MIO (JP)
KATO YASUHARU (JP)
KINOSHITA KAZUTOMO (JP)
KITOH YASUSHI (JP)
IKEDA TAKUMA (JP)
HANEISHI TSUYOSHI (JP)
MARUYAMA NORIAKI (JP)
KOBAYASHI MIO (JP)
Application Number:
PCT/JP2006/323891
Publication Date:
June 07, 2007
Filing Date:
November 30, 2006
Export Citation:
Assignee:
CHUGAI PHARMACEUTICAL CO LTD (JP)
KAWASE AKIRA (JP)
KATO YASUHARU (JP)
KINOSHITA KAZUTOMO (JP)
KITOH YASUSHI (JP)
IKEDA TAKUMA (JP)
HANEISHI TSUYOSHI (JP)
MARUYAMA NORIAKI (JP)
KOBAYASHI MIO (JP)
KAWASE AKIRA (JP)
KATO YASUHARU (JP)
KINOSHITA KAZUTOMO (JP)
KITOH YASUSHI (JP)
IKEDA TAKUMA (JP)
HANEISHI TSUYOSHI (JP)
MARUYAMA NORIAKI (JP)
KOBAYASHI MIO (JP)
International Classes:
C07C401/00; C07J41/00; C07J71/00
Domestic Patent References:
| WO2001096293A1 | 2001-12-20 | |||
| WO2001079166A1 | 2001-10-25 | |||
| WO2001096293A1 | 2001-12-20 | |||
| WO1998028266A1 | 1998-07-02 | |||
| WO1998028266A1 | 1998-07-02 |
Foreign References:
| JPH10231284A | 1998-09-02 |
Other References:
See also references of EP 1961740A4
CHEM. PHARM. BULL., vol. 40, no. 5, 1992, pages 1120 - 4
ORG. PROCESS. DEV., vol. 9, 2005, pages 278 - 287
"Protective Groups in Organic Synthesis", 1991, JOHN WILEY & SONS
ORG. PROCESS. RES. DEV., vol. 9, 2005, pages 278 - 287
CHEM. PHARM. BULL., vol. 40, no. 5, 1992, pages 1120 - 4
ORG. PROCESS. DEV., vol. 9, 2005, pages 278 - 287
"Protective Groups in Organic Synthesis", 1991, JOHN WILEY & SONS
ORG. PROCESS. RES. DEV., vol. 9, 2005, pages 278 - 287
Attorney, Agent or Firm:
SHAMOTO, Ichio et al. (Section 206 New Ohtemachi Bldg., 2-1, Ohtemachi 2-chome, Chiyoda-k, Tokyo 04, JP)
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