METHOD OF PURIFYING POLYPEPTIDES BY SIMULATED MOVING BED CHROMATOGRAPHY

Title:

METHOD OF PURIFYING POLYPEPTIDES BY SIMULATED MOVING BED CHROMATOGRAPHY

Document Type and Number:

WIPO Patent Application WO2004024284

Kind Code:

A3

Abstract:

Provided are methods of separating an immunoreactive compound from at least one immaterial component, using a simulated moving bed ("SMB") system and a SMB apparatus for use in these methods. Also provided are purified immunoreactive compounds prepared using the SMB methods and apparatus and methods of treatment with the purified immunoreactive compounds.

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Inventors:

THOEMMES JOERG P (US)
SONNENFELD ALAN M (US)
PIERACCI JOHN P (US)
CONLEY LYNN (US)
BISSCHOPS MARC (NL)
PENNINGS MAARTEN (NL)

Application Number:

PCT/US2003/028809

Publication Date:

September 23, 2004

Filing Date:

September 12, 2003

Export Citation:

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Assignee:

IDEC PHARMA CORP (US)
THOEMMES JOERG P (US)
SONNENFELD ALAN M (US)
PIERACCI JOHN P (US)
CONLEY LYNN (US)
BISSCHOPS MARC (NL)
PENNINGS MAARTEN (NL)

International Classes:

B01D15/18; C07K1/16; G01N30/02; G01N33/558; G01N30/46; (IPC1-7): A61K38/00

Foreign References:

US5770088A	1998-06-23
US20030149081A1	2003-08-07

Other References: