Title:
METHOD FOR PURIFYING URSODEOXYCHOLIC ACID
Document Type and Number:
WIPO Patent Application WO/2023/280313
Kind Code:
A1
Abstract:
Disclosed is a method for purifying ursodeoxycholic acid (UDCA), comprising the following steps: step A sets forth the preparation of 4-dimethylpyridine ammonium salt of UDCA; and step B sets forth the hydrolysis of the 4-dimethylpyridine ammonium salt of UDCA. In the present invention, operation is simple, solvents and reagents used are low in cost and readily available, the present invention is suitable for industrial production, and the purity of the obtained UDCA is high.
Inventors:
QIU WENWEI (CN)
LI CHENCHEN (CN)
GU XIANGZHONG (CN)
JIANG CHENGYU (CN)
WU SHULAN (CN)
LIN LIN (CN)
LI CHENCHEN (CN)
GU XIANGZHONG (CN)
JIANG CHENGYU (CN)
WU SHULAN (CN)
LIN LIN (CN)
Application Number:
PCT/CN2022/104683
Publication Date:
January 12, 2023
Filing Date:
July 08, 2022
Export Citation:
Assignee:
UNIV EAST CHINA NORMAL (CN)
JIANGSU JIAERKE PHARMACEUTICALS GROUP CORP LTD (CN)
JIANGSU JIAERKE PHARMACEUTICALS GROUP CORP LTD (CN)
International Classes:
C07J9/00
Foreign References:
| JP2001261696A | 2001-09-26 | |||
| CN110669091A | 2020-01-10 | |||
| CN101987860A | 2011-03-23 | |||
| CN101215310A | 2008-07-09 | |||
| CN106928306A | 2017-07-07 | |||
| CN113480589A | 2021-10-08 |
Attorney, Agent or Firm:
MSJLAW OFFICE (CN)
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