Title:
METHOD AND REAGENT FOR NUCLEIC ACID EXTRACTION AND PURIFICATION USING POROUS NANOMATERIAL
Document Type and Number:
WIPO Patent Application WO/2023/227093
Kind Code:
A1
Abstract:
A method for extracting nucleic acids from a biological sample (such as plasma) using nanopores in a porous material. The method induces nucleic acids into nanopores of the porous material to achieve separation and purification of nucleic acids. The method also has the advantage that the bound nucleic acids will not separate from the pores under separation and cleaning conditions, and thus has good application prospects. The material containing nanopores can have added paramagnetic cores (for example, magnetic microspheres of ferroferric oxide) and be applied to a full-automatic nucleic acid extraction workstation to improve nucleic acid extraction efficiency.
Inventors:
LIU JUN (CN)
DING QIUTAO (CN)
CHENG YANCHAO (CN)
JIA XINYE (CN)
HUANG YUCHEN (CN)
MENG XIN (CN)
ZHANG QIONGLU (CN)
CHEN CHENGTONG (CN)
SHI XIAOYU (CN)
DING QIUTAO (CN)
CHENG YANCHAO (CN)
JIA XINYE (CN)
HUANG YUCHEN (CN)
MENG XIN (CN)
ZHANG QIONGLU (CN)
CHEN CHENGTONG (CN)
SHI XIAOYU (CN)
Application Number:
PCT/CN2023/096451
Publication Date:
November 30, 2023
Filing Date:
May 26, 2023
Export Citation:
Assignee:
HANGZHOU NEW HORIZON HEALTH TECH CO LTD (CN)
International Classes:
C12N15/10
Foreign References:
| EP1260595A2 | 2002-11-27 | |||
| CN102327622A | 2012-01-25 | |||
| CN116550303A | 2023-08-08 | |||
| CN109706056A | 2019-05-03 |
Attorney, Agent or Firm:
WU , FENG & ZHANG (CN)
Download PDF: