Title:
METHOD FOR REDUCING MEASUREMENT ERRORS DUE TO HEMOLYZED HEMOGLOBIN
Document Type and Number:
WIPO Patent Application WO/2023/085323
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a method for reducing measurement errors caused by hemolyzed hemoglobin. The method of the present invention comprises treating a biological component in a sample or a substance derived from the biological component with an oxidase, and reacting the hydrogen peroxide thus generated with a color former in the presence of a peroxidase followed by colorimetric determination, wherein measurement errors caused by hemolyzed hemoglobin are reduced by the action of at least one nonionic surfactant selected from the group consisting of a glucamine nonionic surfactant and a polyoxyethylene nonionic surfactant having an HLB value of 12.7-13.6.
Inventors:
KINAI MIZUKI (JP)
Application Number:
PCT/JP2022/041727
Publication Date:
May 19, 2023
Filing Date:
November 09, 2022
Export Citation:
Assignee:
TOYO BOSEKI (JP)
International Classes:
C12Q1/28; C12Q1/26
Domestic Patent References:
| WO2013147309A1 | 2013-10-03 |
Foreign References:
| CN109706218A | 2019-05-03 | |||
| JPH11103888A | 1999-04-20 | |||
| JPS6427499A | 1989-01-30 | |||
| JPH09224697A | 1997-09-02 |
Other References:
WIDMANN, C ET AL.: "In vitro activity of MEKK2 and MEKK3 in detergents is a function of a valine to serine difference in the catalytic domain", BIOCHIMICA ET BIOPHYSICA ACTA. PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY, ELSEVIER, AMSTERDAM; NL, vol. 1547, no. 1, 5 May 2001 (2001-05-05), AMSTERDAM; NL , pages 167 - 173, XP004239384, ISSN: 0167-4838, DOI: 10.1016/S0167-4838(01)00183-2
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