Title:
METHOD OF REMOVING ABNORMAL PRION FROM BLOOD PREPARATION
Document Type and Number:
WIPO Patent Application WO/2008/007465
Kind Code:
A1
Abstract:
[PROBLEMS] To provide a method of conveniently and efficiently removing an abnormal prion from a blood preparation. To provide a method whereby an abnormal prion and leucocytes can be simultaneously removed. [MEANS FOR SOLVING PROBLEMS] A method of removing an abnormal prion from a blood preparation characterized by comprising filtering the blood preparation through a filter packed with a support coated with a polymer, which is composed of three units including 20% by mol or more but not more than 40% by mol of a unit originating in a hydrophobic polymerizable monomer, 5% by mol or more but not more than 13% by mol of a unit originating in a polymerizable monomer having a basic nitrogen-containing moiety, and a unit originating in a polymerizable monomer having a protonic neutral hydrophilic moiety as the balance, and then recovering the filtered blood preparation.
Inventors:
NIRASAWA HIROMI (JP)
MIURA MORIKAZU (JP)
MIURA MORIKAZU (JP)
Application Number:
PCT/JP2007/000755
Publication Date:
January 17, 2008
Filing Date:
July 12, 2007
Export Citation:
Assignee:
ASAHI KASEI MEDICAL CO LTD (JP)
NIRASAWA HIROMI (JP)
MIURA MORIKAZU (JP)
NIRASAWA HIROMI (JP)
MIURA MORIKAZU (JP)
International Classes:
A61K35/14; A61J3/00; A61M1/02; A61M1/34; A61M1/36; A61P7/00
Domestic Patent References:
| WO2003011924A1 | 2003-02-13 | |||
| WO2002060557A1 | 2002-08-08 | |||
| WO2003011924A1 | 2003-02-13 |
Foreign References:
| JP2003190276A | 2003-07-08 | |||
| JP2006095139A | 2006-04-13 | |||
| JP2001276181A | 2001-10-09 | |||
| US20050014196A1 | 2005-01-20 | |||
| JP2002539081A | 2002-11-19 | |||
| JP2006522344A | 2006-09-28 |
Other References:
GCHAZOT ET AL., LANCET, vol. 347, 1996, pages 1181
R.GWILL ET AL., LANCET, vol. 347, 1996, pages 921 - 25
"Guide to the preparation, use and quality assurance of blood components", COUNCIL OF EUROPE PUBLISHING
J BRANDRUP; E.H.IMMERGUT.: "Polymer Hand book", 1989, A WILLEY-INTERSCIENCE PUBLICATION, pages: VII-5 - VII-18
SAMUEL COKER: "Cambridge Healthtech Institut's 10th Annual Transmissible Spongiform Encephalopathies", THE DEFINITIVE AMERICAN TSE MEETING, March 2006 (2006-03-01)
CLIN. BIOCHEM., vol. 8, 1975, pages 96 - 102
SPEARMAN, BRIT. J. OF PSYCHOLOGY, vol. 2, 1908, pages 227 FF
KAERBER, NAUNYN SCHMIEDEBERG'S ARHC. EXP. PATH. PHARMAK., vol. 152, 1931, pages 380 FF
R.GWILL ET AL., LANCET, vol. 347, 1996, pages 921 - 25
"Guide to the preparation, use and quality assurance of blood components", COUNCIL OF EUROPE PUBLISHING
J BRANDRUP; E.H.IMMERGUT.: "Polymer Hand book", 1989, A WILLEY-INTERSCIENCE PUBLICATION, pages: VII-5 - VII-18
SAMUEL COKER: "Cambridge Healthtech Institut's 10th Annual Transmissible Spongiform Encephalopathies", THE DEFINITIVE AMERICAN TSE MEETING, March 2006 (2006-03-01)
CLIN. BIOCHEM., vol. 8, 1975, pages 96 - 102
SPEARMAN, BRIT. J. OF PSYCHOLOGY, vol. 2, 1908, pages 227 FF
KAERBER, NAUNYN SCHMIEDEBERG'S ARHC. EXP. PATH. PHARMAK., vol. 152, 1931, pages 380 FF
Attorney, Agent or Firm:
ISHII, Yoshio et al. (4F. 7-7, Toranomon 2-chome, Minato-k, Tokyo 01, JP)
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