METHOD AND SYSTEM FOR GENERAL PURPOSE ANALYSIS OF EXPERIMENTAL DATA

WIPO Patent Application WO2000072258

A3

Methods and system for general purpose analysis of images acquired from experimental data collected with automated feature-rich, high-throughput experimental data collection systems. A set of pre-determined general assay features is presented. An assay feature includes one or more measurements for an object in a digital photographic image acquired from the experimental data. The set of pre-determined general assay features includes object features, aggregate features and general purpose image processing features. A set of desired assay features is selected from the set of features. A set of images is processed using the desired assay features from the selected set of assay features. The methods and system help provide a general purpose assay development tool. The methods and system allow a biologist, other scientist or lab technician not trained in image processing techniques to quickly and easily design protocols and assays to analyze images acquired from experimental data (e.g., cells). The methods and system may improve the identification, selection, validation and screening of new drug compounds that have been applied to populations of cells. The methods and system may also be used to provide new bioinformatic techniques to manipulate experimental data including multiple digital photographic images.

GOUGH ALBERT H (US)
LAPETS OLEG P (US)
BRIGHT GARY (US)

PCT/US2000/014246

May 31, 2001

May 24, 2000

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CELLOMICS INC (US)
GOUGH ALBERT H (US)
LAPETS OLEG P (US)
BRIGHT GARY (US)

C12M1/00; G01N33/48; C12Q1/02; G01N15/02; G06T1/00; G06T7/60; (IPC1-7): G06T7/60

US5235522A

1993-08-10

See also references of EP 1138019A2

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