Title:
METHOD AND SYSTEM FOR STUDYING BIOLOGICAL CELLS
Document Type and Number:
WIPO Patent Application WO/2018/083193
Kind Code:
A3
Abstract:
A method of manipulating and/or investigating cellular bodies (9) is provided. The method comprises the steps of: providing a sample holder (3) comprising a holding space (5) for holding a fluid medium (11); providing a sample (7) comprising one or more cellular bodies (9) in a fluid medium (11) in the holding space (5); generating an acoustic wave in the holding space exerting a force (F) on the sample (7) in the holding space (5). The method further comprises providing the holding space (5) with a functionalised wall surface portion (17) to be contacted by the sample (7) and the sample (7) is in contact with the functionalised wall surface portion (17) during at least part of the step of application of the acoustic wave. A system and a sample holder (3) are also provided.
Inventors:
CANDELLI ANDREA (NL)
OSWALD FELIX (NL)
SITTERS GERRIT (NL)
OSWALD FELIX (NL)
SITTERS GERRIT (NL)
Application Number:
PCT/EP2017/078090
Publication Date:
May 09, 2019
Filing Date:
November 02, 2017
Export Citation:
Assignee:
LUMICKS TECH B V (NL)
International Classes:
G01N29/22; B01L3/00; G01N21/03; G01N21/17; G01N21/64; G01N29/036; G01N29/24; G01N29/34
Foreign References:
| US20070184433A1 | 2007-08-09 | |||
| US20110207238A1 | 2011-08-25 | |||
| US7081192B1 | 2006-07-25 |
Other References:
SIDDIQUE A K ET AL: "Use of frequency swept ultrasound to manipulate Nb2-11 live cells in a microfluidic channel", JOURNAL OF THE KOREAN PHYSICAL SOCIETY, KOREAN PHYSICAL SOCIETY, KR, vol. 64, no. 2, 7 February 2014 (2014-02-07), pages 226 - 231, XP035352516, ISSN: 0374-4884, [retrieved on 20140207], DOI: 10.3938/JKPS.64.226
Attorney, Agent or Firm:
DE VRIES & METMAN et al. (NL)
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