Title:
METHOD FOR TESTING ON RISK OF CARDIAC INFARCTION
Document Type and Number:
WIPO Patent Application WO/2010/010697
Kind Code:
A1
Abstract:
Disclosed are: a highly reliable, clinically useful method for testing on the risk of cardiac infarction; and a reagent and a kit for use in the method. A single nucleotide polymorphism specified by rs6546820, rs10191517, rs7560272, rs7604588, rs6718864, rs6706179, rs7573719, rs6720094, rs6740173, rs6748040, rs6546829, rs1881246, rs12996463, rs2178154, rs1528169, rs1406105, rs6749680, rs1246105, rs780395, rs1246096, rs3820700, rs7598660, rs11685372, rs6744697, rs13008860, rs17349804, rs7566315, rs2948441, rs4852937, rs7570014, rs4241256, rs4852940, rs2421588, rs4852951, rs4852959, rs2421669, rs2421581, rs4511748, rs2421574, rs7608328, rs2947845, rs1815028, rs4852978, rs2006997, rs7210, rs11126416, rs2272178, rs12624267, rs2421559, rs2272051, rs2462127, rs3813229, rs6546875 or rs1036113 is detected in a nucleic acid sample collected from a subject to determine or assess the risk of cardiac infarction in the subject.
Inventors:
YOKOTA MITSUHIRO (JP)
ASANO HIROYUKI (JP)
ASANO HIROYUKI (JP)
Application Number:
PCT/JP2009/003445
Publication Date:
January 28, 2010
Filing Date:
July 22, 2009
Export Citation:
Assignee:
YOKOTA MITSUHIRO (JP)
ASANO HIROYUKI (JP)
ASANO HIROYUKI (JP)
International Classes:
C12Q1/68; C12N15/09
Other References:
MITSUHIRO YOKOTA ET AL.: "Shinkin Kosoku no Genome Ekigaku", GENOME MEDICINE, vol. 5, no. 4, 2005, pages 341 - 346
YAMADA Y. ET AL.: "Molecular genetics of myocardial infarction.", GENOMIC MED., vol. 2, no. 1-2, January 2008 (2008-01-01), pages 7 - 22
TANAKA T. ET AL.: "Genomewide linkage and linkage disequilibrium analyses identify COL6A1, on chromosome 21, as the locus for ossification of the posterior longitudinal ligament of the spine.", AM. J. HUM. GENET., vol. 73, no. 4, 2003, pages 812 - 822
TOSHIHIRO TANAKA ET AL.: "Tahomen kara no Kaiseki Approach ni yoru Kojujintai Kokkasho no Kanjusei Idenshi Dotei o Mezashite", HONE· KANSETSU·JINTAI, vol. 20, no. 9, 2007, pages 875 - 885
YAMADA Y. ET AL.: "Molecular genetics of myocardial infarction.", GENOMIC MED., vol. 2, no. 1-2, January 2008 (2008-01-01), pages 7 - 22
TANAKA T. ET AL.: "Genomewide linkage and linkage disequilibrium analyses identify COL6A1, on chromosome 21, as the locus for ossification of the posterior longitudinal ligament of the spine.", AM. J. HUM. GENET., vol. 73, no. 4, 2003, pages 812 - 822
TOSHIHIRO TANAKA ET AL.: "Tahomen kara no Kaiseki Approach ni yoru Kojujintai Kokkasho no Kanjusei Idenshi Dotei o Mezashite", HONE· KANSETSU·JINTAI, vol. 20, no. 9, 2007, pages 875 - 885
Attorney, Agent or Firm:
HAGINO, Mikiharu (JP)
Kanji Hagino (JP)
Kanji Hagino (JP)
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