METHOD OF TREATING ARTHRITIS USING LENTIVIRAL VECTORS IN GENE THERAPY

Title:

METHOD OF TREATING ARTHRITIS USING LENTIVIRAL VECTORS IN GENE THERAPY

Document Type and Number:

WIPO Patent Application WO2002083080

Kind Code:

A3

Abstract:

Novel methods for treating and preventing arthritis, such as rheumatoid arthritis, are disclosed which employ lentiviral gene delivery vectors, including HIV-based lentiviral vectors, to deliver a therapeutic gene to a subject. Lentiviral-based vectors treat arthritis by promoting high-level expression of the transferred therapeutic gene in the target tissue of the subject.

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Inventors:

PAWLIUK ROBERT (US)
LEBOULCH PHILIPPE (US)

Application Number:

PCT/US2002/008600

Publication Date:

February 20, 2003

Filing Date:

March 19, 2002

Export Citation:

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Assignee:

GENETIX PHARMACEUTICALS INC (US)
PAWLIUK ROBERT (US)
LEBOULCH PHILIPPE (US)

International Classes:

A61K48/00; C07K14/54; C12N15/867; (IPC1-7): A61K48/00; A61K35/00; C12N5/00; C12N15/63

Domestic Patent References:

WO2001013960A1

2001-03-01

Foreign References:

US6315992B1	2001-11-13
US6258789B1	2001-07-10

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