METHOD OF TREATING COGNITIVE DECLINE DUE TO SLEEP DEPRIVATION AND STRESS

Title:

METHOD OF TREATING COGNITIVE DECLINE DUE TO SLEEP DEPRIVATION AND STRESS

Document Type and Number:

WIPO Patent Application WO2004062616

Kind Code:

A3

Abstract:

This invention relates to methods of use for AMPA receptor potentiator compounds and pharmaceutical compositions in the prevention and treatment of cognitive impairment as a result of acute or chronic sleep deprivation, including enhancement of receptor functioning at synapses in brain networks responsible for higher order behaviors. A still further aspect of the present invention is the use of an active agent as described above for the preparation of a medicament for the treatment of a disorder as described above.

Inventors:

DEADWYLER SAM A (US)
HAMPSON ROBERT E (US)
PORRINO LINDA J (US)
ROGERS GARY A (US)
LYNCH GARY S (US)

Application Number:

PCT/US2004/000706

Publication Date:

December 15, 2005

Filing Date:

January 13, 2004

Export Citation:

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Assignee:

CORTEX PHARMA INC (US)
UNIV WAKE FOREST HEALTH SCIENCES (US)
UNIV CALIFORNIA (US)
DEADWYLER SAM A (US)
HAMPSON ROBERT E (US)
PORRINO LINDA J (US)
ROGERS GARY A (US)
LYNCH GARY S (US)

International Classes:

A61K9/20; A61K31/00; A61K31/18; A61K31/381; A61K31/395; A61K31/4015; A61K31/454; A61K31/497; A61K31/498; A61K31/535; A61K31/5365; A61K31/5377; A61K31/549; A61M1/00; A61P25/20; A61K; (IPC1-7): A61K31/535

Foreign References:

US6313115B1	2001-11-06
US6110935A	2000-08-29

Other References: