Title:
METHODS FOR ANTIBODY OPTIMIZATION
Document Type and Number:
WIPO Patent Application WO/2023/078420
Kind Code:
A1
Abstract:
Provided are methods for antibody engineering. In one aspect, the methods involve a computer-aided method for high-efficiency antibody engineering optimization.
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Inventors:
XIONG BOJIAN (CN)
DONG CHUNFA (CN)
ZHANG HONG (CN)
WANG LUQUAN (CN)
DONG CHUNFA (CN)
ZHANG HONG (CN)
WANG LUQUAN (CN)
Application Number:
PCT/CN2022/130024
Publication Date:
May 11, 2023
Filing Date:
November 04, 2022
Export Citation:
Assignee:
VIBRANT PHARMA LTD (CN)
International Classes:
C07K16/00; G06F30/20
Foreign References:
| US20200377590A1 | 2020-12-03 | |||
| US20130281314A1 | 2013-10-24 | |||
| CN101928345A | 2010-12-29 | |||
| US20070244652A1 | 2007-10-18 |
Other References:
HUANG，J.F. ET AL.: "Template-based protein structure prediction", ACTA BIOPHYSICA SINICA, BIOPHYSICAL SOCIETY OF CHINA, CN, vol. 27, no. 1, 31 January 2011 (2011-01-31), CN , pages 28 - 37, XP009545329, ISSN: 1000-6737
WANG, Z.H. ET AL.: "Gene construction of anti PAF single chain antibody and its protein 3D modeling", HUAZHONG KEJI DAXUE XUEBAO (ZIRAN KEXUE BAN)/JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (NATURAL SCIENCE EDITION), HUAZHONG KEJI DAXUE, CN, vol. 32, no. 6, 30 June 2004 (2004-06-30), CN , pages 114 - 116, XP009545993, ISSN: 1671-4512, DOI: 10.13245/j.hust.2004.06.040
WANG, Z.H. ET AL.: "Gene construction of anti PAF single chain antibody and its protein 3D modeling", HUAZHONG KEJI DAXUE XUEBAO (ZIRAN KEXUE BAN)/JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (NATURAL SCIENCE EDITION), HUAZHONG KEJI DAXUE, CN, vol. 32, no. 6, 30 June 2004 (2004-06-30), CN , pages 114 - 116, XP009545993, ISSN: 1671-4512, DOI: 10.13245/j.hust.2004.06.040
Attorney, Agent or Firm:
MERITS IP LTD. (CN)
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