Title:
METHODS AND APPARATUS FOR DRUG DELIVERY USING SUPERCRITICAL SOLUTIONS
Document Type and Number:
WIPO Patent Application WO/1993/017665
Kind Code:
A1
Abstract:
Methods and apparatus for delivering physiologically active compounds to a target human or animal employ a supercritical fluid solution comprising a supercritical fluid solvent and a physiologically active solute. The supercritical fluid solution is passed into a subcritical region to evaporate the solvent and form a gas-borne dispersion of solute particles. The gas-borne dispersion of solute particles is administered directly to the target human or animal. The apparatus for delivering the physiologically active compound are of the hand-held type.
Inventors:
SIEVERS ROBERT E (US)
HYBERSTON BROOKS M (US)
HANSEN BRIAN N (US)
HYBERSTON BROOKS M (US)
HANSEN BRIAN N (US)
Application Number:
PCT/US1993/001501
Publication Date:
September 16, 1993
Filing Date:
February 19, 1993
Export Citation:
Assignee:
SIEVERS ROBERT E (US)
HYBERSTON BROOKS M (US)
HANSEN BRIAN N (US)
HYBERSTON BROOKS M (US)
HANSEN BRIAN N (US)
International Classes:
A61K9/12; A61K9/16; A61K49/00; A61M15/00; B01F23/00; B01F23/30; B01J3/00; B05B7/32; B05D1/02; C09K3/30; (IPC1-7): A61K9/00; A61K9/12
Domestic Patent References:
| WO1990003782A2 | 1990-04-19 |
Foreign References:
| US4582731A | 1986-04-15 | |||
| EP0008454A2 | 1980-03-05 |
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