Title:
METHODS AND APPARATUS FOR THE SELECTION AND/OR PROCESSING OF PARTICLES, IN PARTICULAR FOR THE SELECTIVE AND/OR OPTIMISED LYSIS OF CELLS
Document Type and Number:
WIPO Patent Application WO2007116312
Kind Code:
A8
Abstract:
Methods and apparatus for the selection or processing of particles sensitive to the application of an external stimulus, in which is produced, by applying the external stimulus, the rupture/lysis of at least one selected particle or the fusion of first and second selected particles, by means of the organisation of the particles (CELL) using a first field of force (FMAN) by selectively energising electrodes (EL) of an array of selectable electrodes having dimensions comparable to or smaller than those of the particles, applying to the electrodes a first configuration (PMAN) of stresses; and by applying to the electrodes a second configuration (PZAP) of stresses, so as to create a second field of force (FZAP), located substantially close to at least one selected particle to be lysated (CELL) or to a pair of first and second particles to be fused and such as to produce the application of a stimulus suited to produce their lysis or fusion.
Inventors:
MANARESI NICOLO (IT)
MEDORO GIANNI (IT)
ABONNENC MELANIE (FR)
MEDORO GIANNI (IT)
ABONNENC MELANIE (FR)
Application Number:
PCT/IB2007/000963
Publication Date:
November 27, 2008
Filing Date:
April 12, 2007
Export Citation:
Assignee:
SILICON BIOSYSTEMS SPA (IT)
MANARESI NICOLO (IT)
MEDORO GIANNI (IT)
ABONNENC MELANIE (FR)
MANARESI NICOLO (IT)
MEDORO GIANNI (IT)
ABONNENC MELANIE (FR)
International Classes:
B03C5/02; B03C5/00
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