Title:
METHODS FOR CLONING AND MANIPULATING GENOMES
Document Type and Number:
WIPO Patent Application WO/2011/109031
Kind Code:
A8
Abstract:
Compositions and methods are disclosed herein for cloning a synthetic or a semi-synthetic donor genome in a heterologous host cell. In one embodiment, the donor genome can be further modified within a host cell. Modified or unmodified genomes can be further isolated from the host cell and transferred to a recipient cell. Methods disclosed herein can be used to alter donor genomes from intractable donor cells in more tractable host cells.
Inventors:
BENDERS GWYNEDD A (US)
GLASS JOHN I (US)
HUTCHISON CLYDE A (US)
LARTIGUE CAROLE (FR)
VASHEE SANJAY (US)
ALGIRE MIKKEL A (US)
SMITH HAMILTON O (US)
MERRYMAN CHARLES E (US)
NOSKOV VLADIMIR N (US)
CHUANG RAY-YUAN (US)
GIBSON DANIEL G (US)
VENTER J CRAIG (US)
GLASS JOHN I (US)
HUTCHISON CLYDE A (US)
LARTIGUE CAROLE (FR)
VASHEE SANJAY (US)
ALGIRE MIKKEL A (US)
SMITH HAMILTON O (US)
MERRYMAN CHARLES E (US)
NOSKOV VLADIMIR N (US)
CHUANG RAY-YUAN (US)
GIBSON DANIEL G (US)
VENTER J CRAIG (US)
Application Number:
PCT/US2010/035490
Publication Date:
September 20, 2012
Filing Date:
May 19, 2010
Export Citation:
Assignee:
SYNTHETIC GENOMICS INC (US)
BENDERS GWYNEDD A (US)
GLASS JOHN I (US)
HUTCHISON CLYDE A (US)
LARTIGUE CAROLE (FR)
VASHEE SANJAY (US)
ALGIRE MIKKEL A (US)
SMITH HAMILTON O (US)
MERRYMAN CHARLES E (US)
NOSKOV VLADIMIR N (US)
CHUANG RAY-YUAN (US)
GIBSON DANIEL G (US)
VENTER J CRAIG (US)
BENDERS GWYNEDD A (US)
GLASS JOHN I (US)
HUTCHISON CLYDE A (US)
LARTIGUE CAROLE (FR)
VASHEE SANJAY (US)
ALGIRE MIKKEL A (US)
SMITH HAMILTON O (US)
MERRYMAN CHARLES E (US)
NOSKOV VLADIMIR N (US)
CHUANG RAY-YUAN (US)
GIBSON DANIEL G (US)
VENTER J CRAIG (US)
International Classes:
C12N15/10; C12N15/74
Attorney, Agent or Firm:
HAILE, Lisa, A. (4365 Executive Drive Suite 110, San Diego CA, US)
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