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Title:
METHODS AND COMBINATION THERAPY TO TREAT CANCER
Document Type and Number:
WIPO Patent Application WO/2019/139581
Kind Code:
A1
Abstract:
This invention relates to a method of treating cancer by administering to a patient in need thereof, over a period of time, therapeutic agents that consist essentially of a MEK inhibitor which is binimetinib or a pharmaceutically acceptable salt thereof, and a PD-1 binding antagonist, to a patient in need thereof.

Inventors:
LEE PATRICE A (US)
CHANTRY DAVID (US)
WINSKI SHANNON L (US)
Application Number:
PCT/US2018/013211
Publication Date:
July 18, 2019
Filing Date:
January 10, 2018
Export Citation:
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Assignee:
LEE PATRICE A (US)
CHANTRY DAVID (US)
WINSKI SHANNON L (US)
International Classes:
A61K31/4184; A61K31/519
Domestic Patent References:
WO2017106656A12017-06-22
Foreign References:
US20170112925A12017-04-27
US20160013654A12016-01-14
US20170209574A12017-07-27
Other References:
See also references of EP 3737373A4
Attorney, Agent or Firm:
REITER, Tiffany et al. (US)
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