Title:
METHODS AND COMPOSITIONS FOR IDENTIFYING RNA-BINDING PROTEINS
Document Type and Number:
WIPO Patent Application WO2005062947
Kind Code:
A3
Abstract:
The present invention includes compositions, methods and kits for the identification of a polypeptide that binds to a predetermined RNA sequence. The invention comprises, in part, a photoreactive moiety to aid in identification of such a polypeptide.
Inventors:
EBERWINE JAMES (US)
LANGEL ULO (SE)
KILK KALLE (SE)
ZIELINSKI JENNIFER (US)
LANGEL ULO (SE)
KILK KALLE (SE)
ZIELINSKI JENNIFER (US)
Application Number:
PCT/US2004/043401
Publication Date:
September 09, 2005
Filing Date:
December 22, 2004
Export Citation:
Assignee:
UNIV PENNSYLVANIA (US)
EBERWINE JAMES (US)
LANGEL ULO (SE)
KILK KALLE (SE)
ZIELINSKI JENNIFER (US)
EBERWINE JAMES (US)
LANGEL ULO (SE)
KILK KALLE (SE)
ZIELINSKI JENNIFER (US)
International Classes:
A61K47/48; C07H21/04; C07K14/00; C07K14/435; C07K14/72; C12N15/11; C12Q1/68; (IPC1-7): C07H21/04; C12N15/11; C12Q1/68
Other References:
LINDGREN ET AL: "Cell-Penetrating Peptides.", TRENDS IN PHARMACOLOGICAL SCIENCE., vol. 21, March 2000 (2000-03-01), pages 99 - 103, XP002290884
WILLIS ET AL: "Photocrosslinking of 5-lodouracil-Substituted RNA and DNA to Proteins.", SCIENCE., vol. 262, 19 November 1993 (1993-11-19), pages 1255 - 1257, XP001206587
WILLIS ET AL: "Photocrosslinking of 5-lodouracil-Substituted RNA and DNA to Proteins.", SCIENCE., vol. 262, 19 November 1993 (1993-11-19), pages 1255 - 1257, XP001206587
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