METHODS AND COMPOSITIONS FOR TREATING CANCER - MASSACHUSETTS INST TECHNOLOGY

Title:

METHODS AND COMPOSITIONS FOR TREATING CANCER

Document Type and Number:

WIPO Patent Application WO2005086974

Kind Code:

A3

Abstract:

The invention provides compounds and methods for treating cancer. Exemplary compounds are multi-functional compounds with two different moieties connected by a linker. Compounds of the invention can activate one or more pathways that results in the inhibition of cell growth. The invention includes cytostatic and cytotoxic compounds. Methods and compositions of the invention are particularly useful for treating cancer cells that are resistanct to other chemotherapeutic drugs.

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Inventors:

ESSIGMANN JOHN M (US)
CROY ROBERT G (US)

Application Number:

PCT/US2005/008330

Publication Date:

February 09, 2006

Filing Date:

March 10, 2005

Export Citation:

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Assignee:

MASSACHUSETTS INST TECHNOLOGY (US)
ESSIGMANN JOHN M (US)
CROY ROBERT G (US)

International Classes:

(IPC1-7): C07C211/00; C07D209/04; C07J1/00

Foreign References:

US4332797A

1982-06-01

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