Title:
METHODS AND COMPOSITIONS FOR TREATING CANCER
Document Type and Number:
WIPO Patent Application WO/2023/230286
Kind Code:
A9
Abstract:
Disclosed herein is a method of treating lymphoma by administering 8-cyclopentyl-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carbonitrile or a pharmaceutically-acceptable salt thereof, alone or in combination with a second agent such a BTK inhibitor, for example ibrutinib, acalabrutinib, or a pharmaceutically-acceptable salt thereof. Also disclosed herein are combinations of 8-cyclopentyl-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carbonitrile or a pharmaceutically-acceptable salt thereof, and second agent such as such a BTK inhibitor, for example ibrutinib or a pharmaceutically-acceptable salt thereof or acalabrutinib or a pharmaceutically-acceptable salt thereof.
Inventors:
FRUCHTMAN STEVEN M (US)
PARRIS MATTHEW (US)
COSENZA STEPHEN C (US)
SILVERSTEIN ADAR MAKOVSKI (US)
ROUÉ GAËL (ES)
GELDER MARK S
PARRIS MATTHEW (US)
COSENZA STEPHEN C (US)
SILVERSTEIN ADAR MAKOVSKI (US)
ROUÉ GAËL (ES)
GELDER MARK S
Application Number:
PCT/US2023/023618
Publication Date:
April 04, 2024
Filing Date:
May 25, 2023
Export Citation:
Assignee:
ONCONOVA THERAPEUTICS INC (US)
International Classes:
C07D487/04; A61P35/00; A61K31/519
Attorney, Agent or Firm:
WONG, Minerva (US)
Download PDF:
Previous Patent: OPEN-CELL FOAM BASED WOUND TREATMENT
Next Patent: BEVERAGE BREWING SYSTEM AND RELATED METHODS
Next Patent: BEVERAGE BREWING SYSTEM AND RELATED METHODS