Title:
METHODS FOR DETECTION OF RARE SUBPOPULATIONS OF CELLS AND HIGHLY PURIFIED COMPOSITIONS OF CELLS
Document Type and Number:
WIPO Patent Application WO/2012/012803
Kind Code:
A3
Abstract:
Methods are provided for detection of a target cell type within a cell population, and compositions are provided comprising cells and an indicator that indicates the number of cells of the target cell type in the cell population. Examples are provided in which these methods are used to detect human embryonic stem cells within a differentiated cell population with exquisite sensitivity. Differentiated cells produced from embryonic stem cells can be characterized by these methods before transplantation into a recipient, thereby providing further assurance of safety.
Inventors:
KLIMANSKAYA IRINA (US)
GAY ROGER J (US)
GAY ROGER J (US)
Application Number:
PCT/US2011/045232
Publication Date:
November 01, 2012
Filing Date:
July 25, 2011
Export Citation:
Assignee:
ADVANCED CELL TECH INC (US)
KLIMANSKAYA IRINA (US)
GAY ROGER J (US)
KLIMANSKAYA IRINA (US)
GAY ROGER J (US)
International Classes:
C12Q1/04; C12N5/071; C12N5/0735; G01N33/533
Domestic Patent References:
| WO2009050657A2 | 2009-04-23 | |||
| WO1999045094A1 | 1999-09-10 |
Foreign References:
| US20100105100A1 | 2010-04-29 | |||
| US20090233324A1 | 2009-09-17 | |||
| US20040133095A1 | 2004-07-08 | |||
| US20050032126A1 | 2005-02-10 |
Other References:
See also references of EP 2596119A4
Attorney, Agent or Firm:
TESKIN, Robin, L. et al. (Intellectual Property Department2200 Pennsylvania Avenue, N.W, Washington District of Columbia, US)
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