Title:
METHODS FOR DIAGNOSING AND TREATING ALZHEIMER'S DISEASE AND PARKINSON'S DISEASE
Document Type and Number:
WIPO Patent Application WO2003007803
Kind Code:
A3
Abstract:
The present invention relates to a method for diagnosing Alzheimer's disease and Parkinson's disease in a subject by analyzing the expression of Semaphorin 3 and downstream effectors. It also provides a method for identifying a substance useful in the prevention or treatment of Alzheimer's disease and Parkinson's disease, and a method of using such substance in the treatment of Alzheimer's disease and Parkinson's disease.
Inventors:
GOOD PAUL F (US)
KOHTZ D STAVE (US)
KOHTZ D STAVE (US)
Application Number:
PCT/US2002/023142
Publication Date:
December 04, 2003
Filing Date:
July 19, 2002
Export Citation:
Assignee:
SINAI SCHOOL MEDICINE (US)
GOOD PAUL F (US)
KOHTZ D STAVE (US)
GOOD PAUL F (US)
KOHTZ D STAVE (US)
International Classes:
C07K16/44; G01N33/68; (IPC1-7): C12Q1/00; C12Q1/68; G01N33/53
Other References:
ARIMURA ET AL.: "Phosphorylation of collapsin response mediator protein-2 by rho-kinase", JBC, vol. 275, 4 August 2000 (2000-08-04), pages 23973 - 23980, XP001094193
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