Title:
METHODS FOR FORMING DYED MICROSPHERES AND POPULATIONS OF DYED MICROSPHERES
Document Type and Number:
WIPO Patent Application WO2006044413
Kind Code:
B1
Abstract:
Various methods for forming dyed microspheres are provided. One method includes activating a chemical structure coupled to a dye using heat or light to form a reaction intermediate in the presence of a microsphere. The reaction intermediate covalently attaches to a polymer of the microsphere thereby coupling the dye to the polymer and forming the dyed microsphere. Additional methods are provided for forming a dyed microsphere coupled to a molecule. These methods include dyeing the microspheres as described above in addition to synthesizing the molecule on an outer surface of the dyed microspheres. A population of dyed microspheres is also provided. Each of the dyed microspheres of the population includes a dye attached to a polymer of each of the dyed microspheres by a chemical structure. A coefficient of variation in dye characteristics of the population of dyed microspheres attributable to the dye is less than about 10%.
Inventors:
HOFFACKER KURT D (US)
LUGADE ANANDA G (US)
TERPETSCHNIG EWALD (US)
LUGADE ANANDA G (US)
TERPETSCHNIG EWALD (US)
Application Number:
PCT/US2005/036571
Publication Date:
August 10, 2006
Filing Date:
October 11, 2005
Export Citation:
Assignee:
LUMINEX CORP (US)
HOFFACKER KURT D (US)
LUGADE ANANDA G (US)
TERPETSCHNIG EWALD (US)
HOFFACKER KURT D (US)
LUGADE ANANDA G (US)
TERPETSCHNIG EWALD (US)
International Classes:
C09B69/10; G01N33/58; G01N33/68
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