Title:
METHODS FOR THE ISOLATION AND PURIFICATION OF ANSAMITOCINS
Document Type and Number:
WIPO Patent Application WO2004015119
Kind Code:
A3
Abstract:
This invention relates to processes for the preparation of ansamitocins, in particular ansamitocins that can be converted to maytansinol.
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Inventors:
FULSTON MARK (GB)
STEFANSKA ANNA L (US)
THIRKETTLE JAN E (GB)
STEFANSKA ANNA L (US)
THIRKETTLE JAN E (GB)
Application Number:
PCT/US2003/024642
Publication Date:
February 16, 2006
Filing Date:
August 07, 2003
Export Citation:
Assignee:
SMITHKLINE BEECHAM CORP (US)
FULSTON MARK (GB)
STEFANSKA ANNA L (US)
THIRKETTLE JAN E (GB)
FULSTON MARK (GB)
STEFANSKA ANNA L (US)
THIRKETTLE JAN E (GB)
International Classes:
C07D491/02; C07D498/14; C12P17/18; (IPC1-7): A61K31/71; C07D491/00; C07D498/16; C07D498/18
Foreign References:
US4322348A | 1982-03-30 | |||
US5676096A | 1997-10-14 | |||
US4361650A | 1982-11-30 | |||
US4162940A | 1979-07-31 | |||
US4228239A | 1980-10-14 | |||
US4356265A | 1982-10-26 | |||
US4294757A | 1981-10-13 | |||
US4145345A | 1979-03-20 |
Other References:
See also references of EP 1627069A4
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