Title:
METHODS AND MATERIALS FOR TREATING CANCER
Document Type and Number:
WIPO Patent Application WO/2020/092736
Kind Code:
A8
Abstract:
This document relates to methods and materials involved in treating mammals having a cancer (e.g., a cancer having one or more CD19 positive extracellular vesicles (EVs) and/or one or more small EVs in the tumor microenvironment). For example, methods of treating a mammal having a blood cancer including one or more CD19 positive EVs and/or one or more small EVs in the blood by administering one or more cancer immunotherapies (e.g., one or more chimeric antigen receptor (CAR) T-cell therapies) to the mammal are provided.
Inventors:
KENDERIAN SAAD J (US)
KAY NEIL E (US)
COX MICHELLE J (US)
LUCIEN-MATTEONI FABRICE (US)
KAY NEIL E (US)
COX MICHELLE J (US)
LUCIEN-MATTEONI FABRICE (US)
Application Number:
PCT/US2019/059113
Publication Date:
November 26, 2020
Filing Date:
October 31, 2019
Export Citation:
Assignee:
MAYO FOUND MEDICAL EDUCATION & RES (US)
International Classes:
A61K48/00; A61K39/00; C12N5/071; C12N5/16; C12N15/00; G01N33/574
Attorney, Agent or Firm:
WILLIS, Margaret S. J. et al. (US)
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