METHODS OF NAD+-DEPENDENT DEACETYLASE INHIBITORS

Title:

METHODS OF NAD+-DEPENDENT DEACETYLASE INHIBITORS

Document Type and Number:

WIPO Patent Application WO2005053609

Kind Code:

A3

Abstract:

The present invention relates to methods of treating cancer, cardiovascular disorders, and neurological disorders using NAD+-dependent deacetylase inhibitors.

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Inventors:

ZHANG JIE (US)
XU WEIZHENG (US)

Application Number:

PCT/US2004/039220

Publication Date:

September 01, 2005

Filing Date:

November 23, 2004

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Assignee:

GUILFORD PHARM INC (US)
ZHANG JIE (US)
XU WEIZHENG (US)

International Classes:

A61K31/12; A61K31/38; A61K31/54; A61K; (IPC1-7): A61K31/54; A61K31/12; A61K31/38

Domestic Patent References:

WO2003007933A1

2003-01-30

Foreign References:

US6511990B1

2003-01-28

Other References:

HODNETT E. ET AL: "Subtituted 1,4-Naphthoquinones vs. the Ascitic Sarcoma 180 of Mice.", J.MED.CHEM., vol. 23, no. 4, 1983, pages 570 - 574, XP002988938

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