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Title:
METHODS AND SYSTEMS FOR DETECTION, IDENTIFICATION AND QUANTITATION OF MACROLIDES AND THEIR IMPURITIES
Document Type and Number:
WIPO Patent Application WO/2005/108984
Kind Code:
A2
Abstract:
The present invention relates to reverse-phase high performance liquid chromatography (RP-HPLC) methods and systems for detecting macrolides as well as detecting, identifying and quantifying impurities in samples containing a macrolide.

Inventors:
LI JIN (US)
THERRIEN JOSEPH (US)
Application Number:
PCT/US2005/016104
Publication Date:
November 17, 2005
Filing Date:
May 06, 2005
Export Citation:
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Assignee:
CHIRON CORP (US)
LI JIN (US)
THERRIEN JOSEPH (US)
International Classes:
G01N30/02; G01N33/00; G01N33/50; G01N30/34; G01N30/70; G01N30/72; (IPC1-7): G01N33/50
Domestic Patent References:
WO2001091758A12001-12-06
WO1998049315A21998-11-05
Other References:
KANFER I ET AL: "Analysis of macrolide antibiotics" JOURNAL OF CHROMATOGRAPHY A, ELSEVIER, AMSTERDAM, NL, vol. 812, no. 1-2, 3 July 1998 (1998-07-03), pages 255-286, XP004127049 ISSN: 0021-9673
DE LA HUEBRA MARIA-JOSE GONZALEZ ET AL: "Comparative study of coulometric and amperometric detection for the determination of macrolides in human urine using high-performance liquid chromatography." ANALYTICAL AND BIOANALYTICAL CHEMISTRY, vol. 375, no. 8, April 2003 (2003-04), pages 1031-1037, XP002412413 ISSN: 1618-2642
Attorney, Agent or Firm:
COLLIER, Steven, W. et al. (Intellectual Property - R338 P.O. Box 809, Emeryville CA, US)
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