Title:
METHODS AND SYSTEMS FOR MAKING MICROTABLETS FOR DRUG DELIVERY
Document Type and Number:
WIPO Patent Application WO/2013/039621
Kind Code:
A3
Abstract:
Methods and systems are provided for making a drag micro tablet. The method includes loading a lyophilization capillary channel with a liquid drug solution; lyophilizing the liquid drug solution in the lyophilizalion capillary channel to produce a lyophilized drug formulation; compressing the lyophilized drug formulation in the !yophilization capillary channel, or in a compression, capillary channel, to form a microtablet: and ejecting the microtablet from the lyophilization capillary channel or compression capillary channel. The methods and systems may provide drug microtablets having improved content uniformity and reduced weight variability.
Inventors:
COPPETA JONATHAN R (US)
DYER ROBERT (US)
STEVENSON CYNTHIA L (US)
DYER ROBERT (US)
STEVENSON CYNTHIA L (US)
Application Number:
PCT/US2012/050244
Publication Date:
May 08, 2014
Filing Date:
August 10, 2012
Export Citation:
Assignee:
ON DEMAND THERAPEUTICS INC (US)
COPPETA JONATHAN R (US)
DYER ROBERT (US)
STEVENSON CYNTHIA L (US)
COPPETA JONATHAN R (US)
DYER ROBERT (US)
STEVENSON CYNTHIA L (US)
International Classes:
A61K9/54
Foreign References:
| US4134943A | 1979-01-16 | |||
| US7449342B2 | 2008-11-11 | |||
| US5556771A | 1996-09-17 | |||
| US20070259348A1 | 2007-11-08 | |||
| US8192659B1 | 2012-06-05 |
Other References:
See also references of EP 2755686A4
Attorney, Agent or Firm:
KING, Kevin, W. et al. (999 Peachtree Street N, Atlanta GA, US)
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