METHODS OF TREATING AUTOPHAGY-ASSOCIATED DISORDERS AND RELATED PHARMACEUTICAL COMPOSITIONS, DIAGNOSTICS, SCREENING TECHNIQUES AND KITS

Title:

METHODS OF TREATING AUTOPHAGY-ASSOCIATED DISORDERS AND RELATED PHARMACEUTICAL COMPOSITIONS, DIAGNOSTICS, SCREENING TECHNIQUES AND KITS

Document Type and Number:

WIPO Patent Application WO/2012/154944

Kind Code:

A3

Abstract:

The invention provides methods of treating autophagy mediated diseases and disorders and related pharmaceutical compositions, diagnostics, screening techniques and kits. In one embodiment, the invention provides a method of determining whether a subject suffers from, or is at risk of developing, and autophagy mediated disease state and/or condition by evaluating LC3 levels.

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Inventors:

DERETIC VOJO (US)
CASTILLO ELISEO (US)
BRADFUTE STEVEN (US)

Application Number:

PCT/US2012/037300

Publication Date:

April 18, 2013

Filing Date:

May 10, 2012

Export Citation:

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Assignee:

STC UNM (US)
DERETIC VOJO (US)
CASTILLO ELISEO (US)
BRADFUTE STEVEN (US)

International Classes:

A61K39/395; A61P29/00

Domestic Patent References:

WO2008036254A2	2008-03-27
WO2011003883A1	2011-01-13
WO2010129681A1	2010-11-11
WO2007003941A1	2007-01-11

Attorney, Agent or Firm:

COLEMAN, Henry, D. (P.C.714 Colorado Avenu, Bridgeport CT, US)

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