Title:
METHODS FOR TREATING MULTIPLE SCLEROSIS
Document Type and Number:
WIPO Patent Application WO2000021513
Kind Code:
A3
Abstract:
Methods for increasing oligodendrocyte survival are disclosed. The methods of the invention are useful for the treatment of Multiple Sclerosis.
Inventors:
SHANKAR L SAI LATHA (US)
TATTON WILLIAM G (US)
TATTON NADINE A (US)
TATTON WILLIAM G (US)
TATTON NADINE A (US)
Application Number:
PCT/US1999/023482
Publication Date:
August 24, 2000
Filing Date:
October 08, 1999
Export Citation:
Assignee:
SHANKAR L SAI LATHA (US)
TATTON WILLIAM G (US)
TATTON NADINE A (US)
TATTON WILLIAM G (US)
TATTON NADINE A (US)
International Classes:
A61K31/00; A61K31/137; (IPC1-7): A61K31/137; A61P25/28
Domestic Patent References:
| WO1996040095A1 | 1996-12-19 | |||
| WO1996022068A2 | 1996-07-25 | |||
| WO1997025421A2 | 1997-07-17 | |||
| WO1997028791A1 | 1997-08-14 |
Other References:
SHANKAR, S. L. (1) ET AL: "R(-)-deprenyl increases survival and process complexity of oligodendrocytes in vitro.", SOCIETY FOR NEUROSCIENCE ABSTRACTS, (1995) VOL. 21, NO. 1-3, PP. 41. MEETING INFO.: 25TH ANNUAL MEETING OF THE SOCIETY FOR NEUROSCIENCE SAN DIEGO, CALIFORNIA, USA NOVEMBER 11-16, 1995, XP000913708
SKETRIS I.S. ET AL: "Drug therapy in multiple sclerosis: A study of Nova Scotia senior citizens.", CLINICAL THERAPEUTICS, (1996) 18/2 (303-318)., XP000913725
RAINE, CEDRIC S.: "The Norton lecture: A review of the oligodendrocyte in the multiple sclerosis lesion.", JOURNAL OF NEUROIMMUNOLOGY, (1997) VOL. 77, NO. 2, PP. 135-152., XP000913739
MITROVIC, BRANISLAVA ET AL: "An in vitro model of oligodendrocyte destruction by nitric oxide and its relevance to multiple sclerosis.", METHODS (ORLANDO), (1996) VOL. 10, NO. 3, PP. 501-513., XP000913720
SKETRIS I.S. ET AL: "Drug therapy in multiple sclerosis: A study of Nova Scotia senior citizens.", CLINICAL THERAPEUTICS, (1996) 18/2 (303-318)., XP000913725
RAINE, CEDRIC S.: "The Norton lecture: A review of the oligodendrocyte in the multiple sclerosis lesion.", JOURNAL OF NEUROIMMUNOLOGY, (1997) VOL. 77, NO. 2, PP. 135-152., XP000913739
MITROVIC, BRANISLAVA ET AL: "An in vitro model of oligodendrocyte destruction by nitric oxide and its relevance to multiple sclerosis.", METHODS (ORLANDO), (1996) VOL. 10, NO. 3, PP. 501-513., XP000913720
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