Title:
METHODS OF USING (2R, 6R)-HYDROXYNORKETAMINE AND (2S, 6S)-HYDROXYNORKETAMINE IN THE TREATMENT OF DEPRESSION, ANXIETY, ANHEDONIA, FATIGUE, SUICIDAL IDEATION, AND POST TRAUMATIC STRESS DISORDERS
Document Type and Number:
WIPO Patent Application WO/2017/165877
Kind Code:
A8
Abstract:
Disclosed is a method of treating Psychotic Depression, Suicidal Ideation, Disruptive Mood Dysregulation Disorder, Persistent Depressive Disorder (Dysthymia), Premenstrual Dysphoric Disorder, Substance/Medication-Induced Depressive Disorder, Depressive Disorder Due to Another Medical Condition, Other Specified Depressive Disorder, Unspecified Depressive Disorder, Separation Anxiety Disorder, Selective Mutism, Specific Phobia, Social Anxiety Disorder (Social Phobia), Panic Disorder, Panic Attack (Specifier), Agoraphobia, Generalized Anxiety Disorder, Substance/Medication-Induced Anxiety Disorder, Anxiety Disorder Due to Another Medical, Other Specified Anxiety Disorder, Unspecified Anxiety Disorder, or fatigue the method including administering a pharmaceutical composition containing an effective amount of an active agent, wherein the active agent is purified (2R,6R)-hydroxynorketamine, purified (2S,6S)-hydroxynorketamine, or a combination thereof, or a pharmaceutically acceptable salt thereof, together with a pharmaceutically acceptable carrier to a patient in need of such treatment.
Inventors:
WAINER IRVING (US)
ZARATE CARLOS (US)
MOADDEL RUIN (US)
GOULD TODD (US)
ZANOS PANOS (US)
THOMAS CRAIG (US)
MORRIS PATRICK (US)
ZARATE CARLOS (US)
MOADDEL RUIN (US)
GOULD TODD (US)
ZANOS PANOS (US)
THOMAS CRAIG (US)
MORRIS PATRICK (US)
Application Number:
PCT/US2017/024238
Publication Date:
October 18, 2018
Filing Date:
March 27, 2017
Export Citation:
Assignee:
US HEALTH (US)
UNIV MARYLAND (US)
UNIV MARYLAND (US)
International Classes:
A61K31/135; A61P25/24; A61P25/28
Attorney, Agent or Firm:
MAXWELL, Leslie-Anne (US)
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