Title:
METHYLPYRAZOLE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/022186
Kind Code:
A1
Abstract:
The present invention relates to a methylpyrazole compound, a pharmaceutical composition comprising same, a preparation method therefor, and use thereof. In particular, the present invention relates to a compound represented by formula (I) or a pharmaceutically acceptable salt, stereoisomer, tautomer or isotope-labeled compound thereof, a pharmaceutical composition comprising same, a preparation method therefor, and use thereof in the preparation of a medicament for preventing or treating PRMT5 activity-related diseases or conditions.
Inventors:
CHEN ZHONGHUI (CN)
MEI HONGJIANG (CN)
HAN XIAOJUN (CN)
TIAN QIANG (CN)
SONG HONGMEI (CN)
GE JUNYOU (CN)
MEI HONGJIANG (CN)
HAN XIAOJUN (CN)
TIAN QIANG (CN)
SONG HONGMEI (CN)
GE JUNYOU (CN)
Application Number:
PCT/CN2023/108081
Publication Date:
February 01, 2024
Filing Date:
July 19, 2023
Export Citation:
Assignee:
SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD (CN)
International Classes:
C07D237/32; A61K31/437; A61K31/4985; A61K31/502; A61K31/5025; A61P35/00; C07D403/10; C07D487/04
Domestic Patent References:
| WO2022192745A1 | 2022-09-15 | |||
| WO2022216645A1 | 2022-10-13 | |||
| WO2022216648A1 | 2022-10-13 | |||
| WO2023059795A1 | 2023-04-13 | |||
| WO2023098439A1 | 2023-06-08 | |||
| WO2023125540A1 | 2023-07-06 | |||
| WO2017153518A1 | 2017-09-14 |
Foreign References:
| CN116178347A | 2023-05-30 | |||
| CN114728912A | 2022-07-08 | |||
| CN101282960A | 2008-10-08 |
Attorney, Agent or Firm:
NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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