Title:
MICELLE COMPRISING BENZIMIDAZOLE-CARBOHYDRATE CONJUGATE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF AS ANTICANCER AGENT OR ANTIVIRAL AGENT
Document Type and Number:
WIPO Patent Application WO/2023/027236
Kind Code:
A1
Abstract:
According to the present invention, provided are a micelle comprising a benzimidazole-carbohydrate conjugate compound represented by chemical formula 1, a preparation method therefor, and a use thereof as an anticancer agent or an antiviral agent. [Chemical formula 1] In chemical formula 1, R1, R2, R3 and X are the same as those defined in the specification and claims.
Inventors:
KIM TAI-SUN (KR)
SONG KEUM-SOO (KR)
KIM JUNG-HUN (KR)
SONG KEUM-SOO (KR)
KIM JUNG-HUN (KR)
Application Number:
PCT/KR2021/013034
Publication Date:
March 02, 2023
Filing Date:
September 24, 2021
Export Citation:
Assignee:
BIOMETRIX TECH INC (KR)
International Classes:
A61K47/54; A61K9/107; A61K31/4184; A61K47/69; A61P31/12; A61P35/00
Foreign References:
| US5767138A | 1998-06-16 | |||
| KR20210075895A | 2021-06-23 |
Other References:
V.D. UMARE, V.N. INGLE, R.K WANARE: "Synthesis of benzimidazolyl-6-amino-β-D-glucopyranoses", ASIAN JOURNAL OF CHEMISTRY, vol. 20, no. 7, 1 January 2008 (2008-01-01), pages 5399 - 5404, XP093039951
SALLAM MOHAMMED A.E., SALEM DALIA M.S.A., LABIB GORGINA M.H., YOUSSEF TREVENA N.M.A., MATSUO KOICHI: "Studies on saccharide benzimidazoles: 2-(β-D-gulofuranosyl)benzimidazole and 2-(β-D-glucofuranosyl)benzimidazole C-nucleoside analogs; synthesis, anomeric configuration and antifouling potency", CARBOHYDRATE RESEARCH, PERGAMON, GB, vol. 496, 1 October 2020 (2020-10-01), GB , pages 108073, XP093039952, ISSN: 0008-6215, DOI: 10.1016/j.carres.2020.108073
BAHRAMI KIUMARS, KHODAEI MOHAMMAD M., NEJATI AKBAR: "Synthesis of 1,2-disubstituted benzimidazoles, 2-substituted benzimidazoles and 2-substituted benzothiazoles in SDS micelles", GREEN CHEMISTRY, ROYAL SOCIETY OF CHEMISTRY, GB, vol. 12, no. 7, 1 January 2010 (2010-01-01), GB , pages 1237, XP093039953, ISSN: 1463-9262, DOI: 10.1039/c000047g
SALLAM MOHAMMED A.E., SALEM DALIA M.S.A., LABIB GORGINA M.H., YOUSSEF TREVENA N.M.A., MATSUO KOICHI: "Studies on saccharide benzimidazoles: 2-(β-D-gulofuranosyl)benzimidazole and 2-(β-D-glucofuranosyl)benzimidazole C-nucleoside analogs; synthesis, anomeric configuration and antifouling potency", CARBOHYDRATE RESEARCH, PERGAMON, GB, vol. 496, 1 October 2020 (2020-10-01), GB , pages 108073, XP093039952, ISSN: 0008-6215, DOI: 10.1016/j.carres.2020.108073
BAHRAMI KIUMARS, KHODAEI MOHAMMAD M., NEJATI AKBAR: "Synthesis of 1,2-disubstituted benzimidazoles, 2-substituted benzimidazoles and 2-substituted benzothiazoles in SDS micelles", GREEN CHEMISTRY, ROYAL SOCIETY OF CHEMISTRY, GB, vol. 12, no. 7, 1 January 2010 (2010-01-01), GB , pages 1237, XP093039953, ISSN: 1463-9262, DOI: 10.1039/c000047g
Attorney, Agent or Firm:
DAE-A INTELLECTUAL PROPERTY CONSULTING (KR)
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