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Title:
MICROBE THAT PRODUCES USEFUL SUBSTANCE, AND PRODUCTION METHOD
Document Type and Number:
WIPO Patent Application WO/2021/220970
Kind Code:
A1
Abstract:
The present invention addresses the problem, to be solved, of improving the productivity of glutathione fermentation by microbes.　The present invention pertains to a microbe strain which is configured for enhanced expression of a gene that codes for serine-O-acetyltransferase (EC:2.3.1.30) and which is capable of excessively expressing γ-glutamylcysteine, bis- γ- glutamylcystine, γ-glutamylcystine, reduced glutathione and/or oxidized glutathione. The present invention also pertains to a method that uses the microbe strain.

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Inventors:
KOBAYASHI SHINGO (JP)
DOJUN NOBUHIKO (JP)
MATSUI MISATO (JP)
TAOKA NAOAKI (JP)
Application Number:
PCT/JP2021/016499
Publication Date:
November 04, 2021
Filing Date:
April 23, 2021
Export Citation:
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Assignee:
KANEKA CORP (JP)
International Classes:
C12N1/21; C12N15/09; C12P21/02
Domestic Patent References:
WO2008126784A12008-10-23
WO2016140349A12016-09-09
Foreign References:
JP2012125170A2012-07-05
JP2014064472A2014-04-17
JP2003169668A2003-06-17
Other References:
SUZUKI, H. ET AL.: "The yliA, -B, -C, and-D genes of escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette", JOURNAL OF BACTERIOLOGY, vol. 187, no. 17, 2005, pages 5861 - 5867, XP008120957, DOI: 10.1128/JB.187.17.5861-5867.2005
Attorney, Agent or Firm:
HIRAKI & ASSOCIATES (JP)
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