Title:
MICROBIAL MEDIUM COMPOSITION FOR PRODUCING RETINOL COMPRISING SURFACTANT AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/182584
Kind Code:
A1
Abstract:
The present application relates to: a method for producing retinol, comprising a step of culturing a microorganism of the genus Yarrowia in a medium containing a nonionic surfactant; a method for increasing retinol production; a method for producing retinoid; a microorganism medium composition of the genus Yarrowia for producing retinol, comprising a nonionic surfactant; and a composition for producing retinol, comprising the microorganism or culture thereof and a nonionic surfactant.
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Inventors:
KIM JAE EUNG (KR)
LEE PETER (KR)
PARK HYE MIN (KR)
LEE DONG PIL (KR)
PARK SEONMI (KR)
LEE PETER (KR)
PARK HYE MIN (KR)
LEE DONG PIL (KR)
PARK SEONMI (KR)
Application Number:
PCT/KR2022/011050
Publication Date:
September 28, 2023
Filing Date:
July 27, 2022
Export Citation:
Assignee:
CJ CHEILJEDANG CORP (KR)
International Classes:
C12P23/00; C12N1/16; C12N1/38; C12N15/81; C12R1/645
Domestic Patent References:
| WO2021078452A1 | 2021-04-29 |
Foreign References:
| KR20200066752A | 2020-06-11 |
Other References:
HU, QIONGYUE ET AL.: "Selective biosynthesis of retinol in S. cerevisiae", BIORESOURCES AND BIOPROCESSING, vol. 9, no. 22, 12 March 2022 (2022-03-12), pages 1 - 14, XP009549063, DOI: 10.1186/s40643-022-00512-8
KIRBY JAMES, NISHIMOTO MINOBU, CHOW RUTHIE W. N., PASUMARTHI VENKATA N., CHAN ROSSANA, CHAN LEANNE JADE G., PETZOLD CHRISTOPHER J.: "Use of Nonionic Surfactants for Improvement of Terpene Production in Saccharomyces cerevisiae", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 80, no. 21, 1 November 2014 (2014-11-01), US , pages 6685 - 6693, XP093095873, ISSN: 0099-2240, DOI: 10.1128/AEM.02155-14
PARK HYEMIN, LEE DONGPIL, KIM JAE-EUNG, PARK SEONMI, PARK JOO HYUN, HA CHEOL WOONG, BAEK MINJI, YOON SEOK-HWAN, PARK KWANG HYUN, L: "Efficient production of retinol in Yarrowia lipolytica by increasing stability using antioxidant and detergent extraction", METABOLIC ENGINEERING, pages 26 - 37, XP055937136, [retrieved on 20220630], DOI: 10.1016/j.ymben.2022.06.001
KIRBY JAMES, NISHIMOTO MINOBU, CHOW RUTHIE W. N., PASUMARTHI VENKATA N., CHAN ROSSANA, CHAN LEANNE JADE G., PETZOLD CHRISTOPHER J.: "Use of Nonionic Surfactants for Improvement of Terpene Production in Saccharomyces cerevisiae", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 80, no. 21, 1 November 2014 (2014-11-01), US , pages 6685 - 6693, XP093095873, ISSN: 0099-2240, DOI: 10.1128/AEM.02155-14
PARK HYEMIN, LEE DONGPIL, KIM JAE-EUNG, PARK SEONMI, PARK JOO HYUN, HA CHEOL WOONG, BAEK MINJI, YOON SEOK-HWAN, PARK KWANG HYUN, L: "Efficient production of retinol in Yarrowia lipolytica by increasing stability using antioxidant and detergent extraction", METABOLIC ENGINEERING, pages 26 - 37, XP055937136, [retrieved on 20220630], DOI: 10.1016/j.ymben.2022.06.001
Attorney, Agent or Firm:
HANOL INTELLECTUAL PROPERTY AND LAW (KR)
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