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Title:
MICROFLUIDIC DEVICE FOR MANUFACTURING BIOSCAFFOLD AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/140719
Kind Code:
A1
Abstract:
An aspect relates to a microfluidic device and use thereof. The microfluidic device of the present invention comprises one or more micro-pillars therein, and thus, when blood flow forms inside the device, shear stress is generated by the micro-pillars, which can lead to thrombosis. The thrombus thus generated is vascularized and, when a wound site is treated therewith, simple wounds, viral infection caused by wounds, and chronic wounds can be remarkably improved, and blood vessels formed in the thrombus are aligned in the direction in which blood flows, and thus, a three-dimensional ECM structure suitable for tissues and organs can be manufactured.

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Inventors:
KANG JOO HUN (KR)
JUNG SUHYUN (KR)
Application Number:
PCT/KR2023/001117
Publication Date:
July 27, 2023
Filing Date:
January 25, 2023
Export Citation:
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Assignee:
ULSAN NAT INST SCIENCE & TECH UNIST (KR)
International Classes:
A61L27/36; A61L15/40; A61L15/42; A61L27/56
Domestic Patent References:
WO2008127732A22008-10-23
WO2021133897A12021-07-01
Foreign References:
KR20180027553A2018-03-14
CN106811411A2017-06-09
KR102049556B12019-11-27
Attorney, Agent or Firm:
Y.P.LEE, MOCK & PARTNERS (KR)
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