Title:
MICROFLUIDIC DEVICE, SYSTEM, KIT, METHOD OF ANALYZING NUCLEIC ACIDS, METHOD OF MANIPULATING NUCLEIC ACIDS, METHOD OF DETECTING BIOMOLECULE, AND METHOD OF ANALYZING BIOMOLECULE
Document Type and Number:
WIPO Patent Application WO/2023/220958
Kind Code:
A1
Abstract:
A microfluidic device, a system, a kit, a method of analyzing nucleic acids, a method of manipulating nucleic acids, a method of detecting a biomolecule, and a method of analyzing a biomolecule. The microfluidic device may include electrically conductive layers, to which an electric field can be applied to control movement of biomolecules associated with the single cell in the device. For example, polar molecules (e.g., RNA) of the cell can be captured (e.g., by barcode molecules) and analyzed with improved efficiency.
Inventors:
CHIU YUNYEN (CN)
QIAN MENGYA (CN)
TANG GUOXIN (CN)
ZHU WENQI (CN)
MA YANHONG (CN)
QIAN MENGYA (CN)
TANG GUOXIN (CN)
ZHU WENQI (CN)
MA YANHONG (CN)
Application Number:
PCT/CN2022/093502
Publication Date:
November 23, 2023
Filing Date:
May 18, 2022
Export Citation:
Assignee:
SINGLERON NANJING BIOTECHNOLOGIES LTD (CN)
International Classes:
G01N33/48; G01N1/28
Foreign References:
| US20220126292A1 | 2022-04-28 | |||
| CN101947124A | 2011-01-19 | |||
| CN113740234A | 2021-12-03 | |||
| US20160252517A1 | 2016-09-01 | |||
| US20170107507A1 | 2017-04-20 | |||
| JP2017072476A | 2017-04-13 |
Attorney, Agent or Firm:
BEYOND ATTORNEYS AT LAW (CN)
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