Title:
MICRONEEDLE FORMULATION AND PREPARATION METHOD FOR MICRONEEDLE PATCH
Document Type and Number:
WIPO Patent Application WO/2024/078319
Kind Code:
A1
Abstract:
Provided is a microneedle formulation, comprising: polyvinyl alcohol, polyvinylpyrrolidone and hydroxyethyl cellulose, wherein the polyvinyl alcohol comprises a first polyvinyl alcohol and a second polyvinyl alcohol, the first polyvinyl alcohol having a viscosity of 2.4-12.3 mPas, and the second polyvinyl alcohol having a viscosity of 17.2-42.6 mPas; and the polyvinylpyrrolidone comprises a first polyvinylpyrrolidone and a second polyvinylpyrrolidone, the first polyvinylpyrrolidone having a molecular weight of 3,500-150,000, and the second polyvinylpyrrolidone having a molecular weight of 210,000-1,500,000. The microneedle formulation can effectively improve the structural strength of a microneedle. Moreover, further provided is a preparation method for a microneedle patch.
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Inventors:
JIANG LIN (CN)
Application Number:
PCT/CN2023/121298
Publication Date:
April 18, 2024
Filing Date:
September 26, 2023
Export Citation:
Assignee:
SHENZHEN QINGLAN BIOTECHNOLOGY CO LTD (CN)
International Classes:
A61K9/00; A61K47/36; A61K47/38; A61K47/58; A61M37/00
Domestic Patent References:
| WO2021047629A1 | 2021-03-18 | |||
| WO2017135290A1 | 2017-08-10 | |||
| WO2017159779A1 | 2017-09-21 |
Foreign References:
| CN106422045A | 2017-02-22 | |||
| CN1520373A | 2004-08-11 | |||
| CN104066475A | 2014-09-24 | |||
| CN110193081A | 2019-09-03 | |||
| CN112472809A | 2021-03-12 | |||
| KR20220004888A | 2022-01-12 |
Other References:
YANG REN-REN: "Research progress in applications of dissolving microneedles", MILITARY MEDICAL SCIENCES, vol. 45, no. 6, 24 June 2021 (2021-06-24), pages 454 - 459, XP093157578, DOI: 10.7644/j.issn.1674•9960.2021.06.011
Attorney, Agent or Firm:
SHENZHEN ZHONGDING INTELLECTUAL PROPERTY AGENCY (CN)
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