Title:
MODIFIED BIOPOLYMER AND APPLICATION THEREOF IN 3D PRINTING
Document Type and Number:
WIPO Patent Application WO/2020/237414
Kind Code:
A1
Abstract:
A modified biopolymer, comprising a biopolymer backbone, and a ureido pyrimidone group and a tyramine group which are grafted on the backbone. A bio-ink comprises a solvent and the modified biopolymer dissolved in the solvent, and further comprises a biological functional component loaded by the modified biopolymer. The viscosity of the modified biopolymer is adjustable with temperature, and the modified polymer can be directly solidified by itself at room temperature to form a gel having good mechanical properties. The bio-ink has good viscosity and biocompatibility, is applicable to 3D printing, can be used for direct printing and forming of a biological scaffold, and avoids additional addition of components harmful to biological components, such as a cross-linking agent.
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Inventors:
RUAN CHANGSHUN (CN)
HE HUIMIN (CN)
LIN ZIFENG (CN)
WU MINGMING (CN)
LI DUO (CN)
HE HUIMIN (CN)
LIN ZIFENG (CN)
WU MINGMING (CN)
LI DUO (CN)
Application Number:
PCT/CN2019/088283
Publication Date:
December 03, 2020
Filing Date:
May 24, 2019
Export Citation:
Assignee:
SHENZHEN INST ADV TECH (CN)
International Classes:
C08H1/00; A61L27/20; A61L27/52; B33Y70/00; B33Y80/00; C08B37/08; C08J3/075
Domestic Patent References:
| WO2018073235A1 | 2018-04-26 | |||
| WO2018055452A1 | 2018-03-29 | |||
| WO2018118862A1 | 2018-06-28 |
Foreign References:
| CN107636049A | 2018-01-26 | |||
| CN107043465A | 2017-08-15 | |||
| US20180264175A1 | 2018-09-20 | |||
| CN104710653A | 2015-06-17 | |||
| EP3067069A1 | 2016-09-14 | |||
| CN109251323A | 2019-01-22 |
Attorney, Agent or Firm:
SHENZHEN ZHONGYI UNION INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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