Title:
MODIFIED CAS12A PROTEIN AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/065867
Kind Code:
A1
Abstract:
The present invention relates to a modified CRISPR-associated protein and a use thereof. More specifically, the present invention relates to a genome editing composition comprising the modified CRISPR-associated protein and an enhancer, a genome editing method using same, and a method for construction of a transformant by using same. The modified CRISPR-associated protein according to the present invention is available as a nuclease having excellent indel efficiency in a CRISPR-Cas system, and exhibits excellent indel efficiency compared to conventional CRISPR-Cas systems, thus finding advantageous applications in gene editing.
Inventors:
PARK JONG JIN (KR)
LEE JUNG HYUK (KR)
LEE JUNG HYUK (KR)
Application Number:
PCT/KR2021/012936
Publication Date:
March 31, 2022
Filing Date:
September 23, 2021
Export Citation:
Assignee:
G FLAS LIFE SCIENCES (KR)
International Classes:
C12N9/22; C12N15/10; C12N15/113; C12N15/63
Domestic Patent References:
| WO2017015015A1 | 2017-01-26 |
Foreign References:
| KR20200097760A | 2020-08-19 | |||
| KR20200026804A | 2020-03-11 | |||
| KR102096604B1 | 2020-04-02 | |||
| KR101896847B1 | 2018-09-07 |
Attorney, Agent or Firm:
RYU, Jong Woo et al. (KR)
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