Title:
MODIFIED FIBROIN
Document Type and Number:
WIPO Patent Application WO/2017/188430
Kind Code:
A1
Abstract:
A modified fibroin including a domain sequence indicated by formula 1: [(A) nmotif-REP]m. The modified fibroin has an amino acid sequence having a reduced glycine residue content compared to naturally-derived fibroin, said reduction being equivalent to at least one glycine residue in REP being replaced by another amino acid residue. [In formula 1, (A) nmotif indicates an amino acid sequence comprising 4-20 amino acid residues. The number of alanine residues relative to the total number of amino acid residues in (A) nmotif is at least 83%. REP indicates an amino acid sequence comprising 10-200 amino acid residues. m indicates an integer between 8 and 300. A plurality of (A) nmotif etc., may be the same amino acid sequence or different amino acid sequences.]
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Inventors:
MORITA KEISUKE (JP)
SUGAHARA JUNICHI (JP)
SUGAHARA JUNICHI (JP)
Application Number:
PCT/JP2017/016917
Publication Date:
November 02, 2017
Filing Date:
April 28, 2017
Export Citation:
Assignee:
SPIBER INC (JP)
KOJIMA IND CORP (JP)
KOJIMA IND CORP (JP)
International Classes:
C07K14/435; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09; D01F4/02
Domestic Patent References:
WO2011113592A1 | 2011-09-22 | |||
WO2003057727A1 | 2003-07-17 |
Other References:
See also references of EP 3450451A4
Attorney, Agent or Firm:
HASEGAWA Yoshiki et al. (JP)
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